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  •  2,4-D is not Agent Orange (0+ / 0-)

    It was a component of Agent Orange, but was not the component(s) in Agent Orange that had high toxicity (2,4,5-T and dioxin contamination).  2,4-D has relatively low toxicity.  Please check your facts.

    Democrats give you the Bill of Rights; Republicans sell you a bill of goods!

    by barbwires on Tue Dec 04, 2012 at 08:33:35 PM PST

    •  It has been checked, numerous times, by many (2+ / 0-)
      Recommended by:
      Don midwest, GreenMother

      different sources. I never said it was Agent Orange. Please read again. I said very clearly that 2,4-D was a defoliant used in Agent Orange. I don't know how I could have been clearer than that. Yes 2,45-T was more toxic than 2,4-D but 2,4-D was nonetheless used in Agent Orange. That's just a fact.

      •  You could have been clearer (1+ / 0-)
        Recommended by:

        By providing that additional context.  

        By simply stating that

        The chemical 2,4-D (the defoliant in Agent Orange used in Vietnam) does not discriminate between plants and will kill "non-target" plants raising concerns of farmers because of the issue of drift.
        You imply -- intentionally or not -- that 2,4-D is what makes Agent Orange so bad and scary and why Agent Orange is still in the news 40 years later.
        •  2,4-D is bad. Make no mistake. It is known to harm (0+ / 0-)

          "non-target organisms" (i.e. animals) and has known health effects in humans.

          The modes of toxicity to animals from the acid, ester and salt forms of 2,4-D are similar. The primary exception is that the
          salt and acid forms can be extreme eye irritants.3 2,4-D is actively secreted by the proximal tubules of the kidney, and tox-
          icity appears to result when renal clearance capacity is exceeded.3 Dose-dependent toxic effects include damage to the
          eye, thyroid, kidney, adrenals, and ovaries or testes.3 In addition, researchers have observed neurotoxicity, reproductive
          toxicity, and developmental toxicity.3 Chlorophenoxy herbicides exhibit a variety of mechanisms of toxicity, including
          dose-dependent cell membrane damage leading to central nervous system toxicity,13 interference with cellular metabo-
          lism involving acetyl-coenzyme A (CoA),13 and uncoupling of oxidative phosphorylation due to either the disrupted CoA
          activity or cellular membrane damage.13
          Signs of Toxicity – Humans

          • No occupational studies were found reporting signs or symptoms following exposure to 2,4-D under normal usage.

          • Symptoms of acute oral exposure to 2,4-D include vomiting, diarrhea, headache, confusion, aggressive or bizarre behavior.
          A peculiar odor is sometimes noted on the breath. Skeletal muscle injury and renal failure may also occur.18 Systemic toxic-
          ity is mainly associated with suicide attempts.18

          • Symptoms following dermal exposure may include irritation, and inhalation exposure may lead to coughing and burn-
          ing sensations in the upper respiratory tract and chest.18 Prolonged exposure may result in dizziness.18 Chlorophenoxy
          compounds such as 2,4-D are quickly absorbed when swallowed, but absorption from dermal or inhalation exposure is

          • Case reports and observational studies provide the majority of information regarding the toxicological effects of 2,4-D
          in incidents involving human poisonings. Researchers compiled the medical cases of 69 people who ingested 2,4-D and
          other chlorophenoxy herbicides; 23 of these patients died.13 Ingestion led to vomiting, abdominal pain, diarrhea, and de-
          velopment of hypotension.13 Peripheral neuromuscular effects including muscle twitching, weakness, and loss of tendon
          reflexes have been reported.13 Neuromuscular effects have lasted several weeks to months and have been permanent in
          some cases.13

          •  You need to look at exposures (0+ / 0-)

            before assuming the potential for harm.  The amount of 2,4-D exceeding the renal clearance threshold in humans is more than 13,000 times that found in workers applying 2,4-D--who are the most exposed sub-population.  

            People drinking 2,4-D or other pesticides (as in the last bullet point you cite) would be at risk, depending on the amount ingested, but one cant protect against either suicidal intention or stupidity.

            Democrats give you the Bill of Rights; Republicans sell you a bill of goods!

            by barbwires on Wed Dec 05, 2012 at 11:49:01 AM PST

            [ Parent ]

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