Skip to main content

View Diary: The looming antibiotic crisis can't be solved by the free market (248 comments)

Comment Preferences

  •  You got a point there. (0+ / 0-)

    Sorry, bad examples. MRSA and clostridium difficile would be better, thanks.

    "We are monkeys with money and guns". Tom Waits

    by northsylvania on Wed Mar 13, 2013 at 04:49:23 AM PDT

    [ Parent ]

    •  c. difficile is a different problem (3+ / 0-)
      Recommended by:
      northsylvania, JerryNA, bogieshadow

      It has a spore form which is not vulnerable to any antibiotic and never has been. Thus, it is very difficult to eradicate with medications and it is not killed by alcohol or hand sanitizers.

      There are only two antibiotics with any effectiveness against it, the inexpensive but problematic metronidozole and the expensive and more effective and better tolerated vancomyacin which is the antibiotic of last resort for many infections.

      There is evidence that it is developing resistance to both of these, but it can be a little hard to tease out because of the spore issue.

      Fry, don't be a hero! It's not covered by our health plan!

      by elfling on Wed Mar 13, 2013 at 08:23:52 AM PDT

      [ Parent ]

      •  Now that is interesting. (0+ / 0-)

        I will have to read up on that.

        "We are monkeys with money and guns". Tom Waits

        by northsylvania on Wed Mar 13, 2013 at 10:25:27 AM PDT

        [ Parent ]

      •  A new approach to C difficile (2+ / 0-)
        Recommended by:
        elfling, JerryNA

        Since C difficile doesn't cause illness unless the spores germinate, researchers have tried using agents that keep the spores from germinating. In mice, at least, a particular bile salt analog has proved very effective for that. You can read the study abstract here

        •  Nice. (2+ / 0-)
          Recommended by:
          JerryNA, Sunspots

          It seems that it's pretty common to have C. difficile spores in one's colon, but that the pH and existing flora of a healthy intestinal tract keep it from doing all that much. It's like having a field... as long as there's healthy grass, seeds that blow over it don't have much foothold. But if you just remove all the grass and leave unexposed dirt, you'll have a plot full of weeds in no time.

          Something like that salt might be helpful to administer along with antibiotics, especially in at-risk patients.

          Fry, don't be a hero! It's not covered by our health plan!

          by elfling on Wed Mar 13, 2013 at 12:52:47 PM PDT

          [ Parent ]

Subscribe or Donate to support Daily Kos.

Click here for the mobile view of the site