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View Diary: The looming antibiotic crisis can't be solved by the free market (248 comments)

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  •  There is an issue of a horse race. New antibiotics (1+ / 0-)
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    are created, bugs develop immunity to them. It used to take 5-10 years, now it takes 2-3. It is a well known problem and people in both academia and industry are looking for solutions. In all likelihood, some solution will e found.

    •  New Antibiotic targets mec Bacterial resistance. (5+ / 0-)

      Just to interject a little reality, bacteria acquire resistance by swapping DNA circles that contain the instructions for resistance (plasmids) with each other, which they do like crazy whenever they come under stress from heat, cold, changes in gas pressure, chemicals, starvation, everything is a cue for a hot bacterial swapfest (conjugation).
             I remember in 2008 the FDA withheld approval from  an antibiotic that specifically blocked the ability of the bacteria to grow the structures used in the plasmid swapping process.  The comment was that there were irregularities in the testing process.
      I remember looking into it further and finding that there had been some recording errors at something like 4 or 5 sites out of more than 500.  It looked like none  of the recording errors bore on the safety or effectiveness of the compound. The side effects reported were the same as the plecebo.

      It really appeared as if the FDA had denied approval because they were waiting for the little bio-tech company that had developed the drug to be sold to a bigger drug company.
      But this drug can prevent the development of resistance to other drugs.  
      Now if I could only remember its name.

      To Goldman Sachs in according to their desires, From us in accordance with the IRS.

      by Bluehawk on Wed Mar 13, 2013 at 10:24:22 AM PDT

      [ Parent ]

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