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View Diary: Monday Night Cancer Club: Milestones and Benchmarks (41 comments)

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  •  thanks, that's great to hear. i have one year (6+ / 0-)

    to see if i can get my bones better, and if not, my cancer doc wants me to take fosamax. wanted to start me on now, but all the side effects freaked me out. i think because still working on the side effects from hormones.

    "It is in the shelter of each other that people live." Irish Proverb

    by Patriot Daily News Clearinghouse on Mon May 06, 2013 at 06:08:24 PM PDT

    [ Parent ]

    •  The bone necrosis side effect (6+ / 0-)

      while real, occurs in a very small percentage of people who take it.  YMMV

      Just found this on wiki re osteonecrosis:

      Although this side effect is uncommon, it occurs primarily in patients being administered intravenous biphosphonates, with most cases being reported in cancer patients.
      There aren't many other side effects.  Someone once told me their mom had heartburn from it, but I never had any problems - just take it and forget about it.  Oh, I forgot, you have to lay down for about 20 minutes after you take it.  That's just to prevent problems w/ heartburn.

      More on estrogen therapy from Merck (emphasis mine)

      Concomitant Use with Estrogen

      Hormone Replacement Therapy
      In two studies (of one and two years’ duration) of postmenopausal osteoporotic women (total: n=853), the safety and tolerability profile of combined treatment with FOSAMAX 10 mg once daily and estrogen ± progestin (n=354) was consistent with those of the individual treatments.


      As for the studies on osteonecrosis, its been a long time since I read them and I'm too lazy to look them up now, but IIRC, in the trials there were only 1% or less of patients in the study groups who developed the problem.  More long term data is now available, but I don't think that risk factor changed a whole lot.

      "If you can't take their money, eat their food, drink their booze and then vote against them, you have no business being up there."

      by Betty Pinson on Mon May 06, 2013 at 06:26:02 PM PDT

      [ Parent ]

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