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View Diary: New drug mimics the beneficial effects of exercise (46 comments)

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  •  You might want to write to Scripps (5+ / 0-)

    Get your name on file. You seem to be an ideal candidate for the initial human trials, which are a few years out, but most likely coming.

    The comments so far have been eye opening. I wrote this diary mostly in snark mode, thinking of those pictures we see on the web of hugely obese people in electric wheelchairs or scooters pulling up to the McDonald's window in between the SUV's and pickup trucks. Pictures that scream, "What are you doing? What about some broccoli instead?"

    But there are clearly genetic and biological and psychological causes behind obesity that snark doesn't cover. That aren't a laughing matter at all, but take the kind of devotion to dutiful exercise you demonstrate, and even then some people are condemned to being overweight by causes they can't control, or can't overcome.

    "The rule of the wise must be absolute . . . rulers ought not to be responsible to the unwise subjects." ~ Professor Leo Strauss

    by antifa on Thu Aug 22, 2013 at 03:53:13 PM PDT

    [ Parent ]

    •  Maybe I will - thanks for the idea. (3+ / 0-)
      Recommended by:
      Got a Grip, guyeda, antifa

      Believe me, I've been tempted to get a custom T-shirt for the gym that would read

      Type II gene
      Lipedema
      Two kids

      If you look better than this at 61,
      I'll get you a dozen roses.



      Is it true? Is it kind? Is it necessary? . . . and respect the dignity of every human being.

      by Wee Mama on Thu Aug 22, 2013 at 03:58:27 PM PDT

      [ Parent ]

      •  You should obviously consult with your (1+ / 0-)
        Recommended by:
        Wee Mama

        physician before agreeing.  Preclinical work is highly exploratory and generally if you don't have an immediate pressing need, participating unnecessarily exposes you to the possibility of being in the category of, "some may experience...".  Even formal clinical trials go in stages whose purpose is to evaluate, (1) the safety implications of medication, (2) whether it has a significant beneficial effect, (3) whether it can have a substantial effect.  You're effectively placing yourself at risk for side effects when the efficacy has yet to be determined.  There's also the possibility that you may get put in the placebo group, which depending on how you view it, may not be so bad:  minimal risk, you may be compensated for participating, and you may get some benefit from the placebo effect.

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