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View Diary: WYFP? Arthroscopic Meniscectomy Edition (174 comments)

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  •  yes, but the generic equivalents (4+ / 0-)
    Recommended by:
    JeffW, escapee, Yo Bubba, ladybug53

    are equivalent. I have heard many people over the years argue that brand names were more potent. I personally believe that is placebo, but who knows. Regardless (or "irregardless" if you are my Republican neighbor who never shuts up) the generic would still provide your relief.
    Clonazepam is a bear to kick for most people as it is so long acting. Glad you didn't get WD's.

    •  From what I have heard, FDA regulations allow (4+ / 0-)
      Recommended by:
      nchristine, bastrop, escapee, Yo Bubba

      generics to vary by up to 10% in strength from the brand name medication (or each other).

      You have watched Faux News, now lose 2d10 SAN.

      by Throw The Bums Out on Sat May 24, 2014 at 07:51:00 PM PDT

      [ Parent ]

      •  That is incorrect. (6+ / 0-)

        FDA requires generics to contain the exact same dosages of a bioequivalent active ingredients, meaning it must be absorbed and processed by the body in exactly the same way.

        The deviation you cite is a misconception based on formulas used to calculate bioequivalence. That has made it's way around popular understanding of generics and hails from Pharma disinformation campaigns against generics. And it's just as incorrect as it was way back when.

        That gets perpetuated now by consumers who believe their generics aren't as strong as the brand names. In my experience (and I know a lot of these people) on the internet they are largely people who abuse prescription narcotics, benzos and stimulants and are grasping at justifications for their tolerances.

        •  All I know is (5+ / 0-)
          Recommended by:
          Yo Bubba, nchristine, bastrop, JeffW, TiaRachel

          that I have to use a mail-order pharmacy (rhymes with Depressed Slips), and that they get whatever's cheapest that buying period.  I've taken several different generics.  Some worked, some just didn't.  It was much easier for me to get the name brand through my local pharmacy, Ballpeen's, to insure some consistency.

          But it isn't available through my mail-order company anymore, or from Ballpeen's, or any other retail pharmacy in Delaware, and they all had the same story: unavailable because it's not being produced any longer.  So we went with another, and you are right: it's a bear.  

          "Republicans are poor losers and worse winners." - My grandmother, sometime in the early 1960s

          by escapee on Sun May 25, 2014 at 05:49:52 AM PDT

          [ Parent ]

          •  If you were using mail order (3+ / 0-)
            Recommended by:
            JeffW, nchristine, escapee

            it possible some of the meds were coming from India and China, in which case there is no FDS standard and quality varies. This is always a gamble.

            As to WD switching benzos, if you switch to a shorter acting one (which all are after clonalepam, the second longest lasting being diazepam (valium) ) then you are going to get WD's and you are going to have to take more. It is also a good way to trigger your body into drug seeking mode because you are feeling awful and you want to feel well, so people tend to take more. I hope they chose diazepam. If it's xanax you might consider asking to switch to valium. Xanax is a should stealing drug when used this way. I have seen it so many times.

            •  Same thing here, in brick-and-mortar pharmacies. (3+ / 0-)
              Recommended by:
              escapee, bastrop, nchristine

              Technically equivalent is just not (always) identical. Sometimes changing the manufacturer doesn't matter, sometimes it causes uncomfortably noticeable side effects. Enough people (including physicians) have noted this that I'm more comfortable assuming that human bodies (& drug metabolism, etc) are complex and not well-enough understood than that all those people are imagining things (because of course drug manufacturing/regulation/etc is straightforward & generally not flawed).

              I know that you who hear my singing make those freedom bells go ringing. And so we keep on while we live, until we have no more to give... Don't you know it's darkest before the dawn. This thought keeps me moving on. Pete Seeger bit.ly/1bwCmhK

              by TiaRachel on Sun May 25, 2014 at 01:44:33 PM PDT

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            •  They did, and I feel much better (2+ / 0-)
              Recommended by:
              bastrop, nchristine

              I've heard too many horror stories about Xanax to take it.  

              "Republicans are poor losers and worse winners." - My grandmother, sometime in the early 1960s

              by escapee on Sun May 25, 2014 at 03:04:23 PM PDT

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    •  Not always. (2+ / 0-)
      Recommended by:
      bastrop, nchristine

      Technically, sure, but not always in action. And it's not just a brand-name placebo effect -- I've noticed differences when the pharmacist has given me generics from a different manufacturer.

      I know that you who hear my singing make those freedom bells go ringing. And so we keep on while we live, until we have no more to give... Don't you know it's darkest before the dawn. This thought keeps me moving on. Pete Seeger bit.ly/1bwCmhK

      by TiaRachel on Sun May 25, 2014 at 01:30:24 PM PDT

      [ Parent ]

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