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View Diary: Overnight News Digest -- "An Electric Version of What?!?" Edition (32 comments)

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  •  Thanks rfall ... (16+ / 0-)

    This is certainly promising.

    The findings pave the way for a new wave of drugs that kill superbugs by bringing down their defensive walls rather than attacking the bacteria itself. It means that in future, bacteria may not develop drug-resistance at all.
    Glad you shared it.

    The good thing about science is that it's true whether or not you believe in it.― Neil deGrasse Tyson

    by maggiejean on Thu Jun 19, 2014 at 09:08:49 PM PDT

    •  VERY good news, however (2+ / 0-)
      Recommended by:
      side pocket, maggiejean
      Researchers investigated a class of bacteria called 'Gram-negative bacteria' which is particularly resistant to antibiotics because of its cells' impermeable lipid-based outer membrane.
      This outer membrane acts as a defensive barrier against attacks from the human immune system and antibiotic drugs. It allows the pathogenic bacteria to survive, but removing this barrier causes the bacteria to become more vulnerable and die.
      Two of the worst resistant bacteria, MRSA and C.difficile, both big sources of lethal hospital acquired infections, are  gram positive, so would not be affected by treatment using the new method.  

      Another very great threat is resistant tuberculosis, an increasing problem threatening a new white plague.  

      MTB is not classified as either Gram-positive  or Gram-negative because it does not have the chemical characteristics of either, although the bacteria do contain peptidoglycan (murein) in their cell wall. If a Gram stain is performed on MTB, it stains very weakly Gram-positive or not at all (cells referred to as "ghosts").
      I can't tell whether this implies that the new approach would or would not work against resistant TB, but I suspect not.

       In any case, per the Science Daily report linked in the diary,

      Researchers investigated Gram-negative bacteria, which cause a vast range of infections, including e-coli, salmonella, gonorrhea, pseudomonas, and meningitis.

      There's no such thing as a free market!

      by Albanius on Fri Jun 20, 2014 at 12:07:51 AM PDT

      [ Parent ]

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