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View Diary: What Does The Swine Flu Outbreak Mean? (332 comments)

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  •  Think logically. What kills people when they have (1+ / 0-)
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    freakofsociety

    a flu. Usually dehydration. We can fix that with IV fluids, with adequate access to health care.

    My loving marriage of 17 years is now a symbol of inequality and discrimination.

    by coigue on Sat Apr 25, 2009 at 09:00:38 AM PDT

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    •  what usually kills folks with influenza (1+ / 0-)
      Recommended by:
      freakofsociety

      is not dehydration but pneumnonia.

      •  here perhaps, but what about in Mexico or other (0+ / 0-)

        areas with severe limitations on health care? I am not argng, I just do not know.

        My loving marriage of 17 years is now a symbol of inequality and discrimination.

        by coigue on Sat Apr 25, 2009 at 09:24:00 AM PDT

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    •  I'd guess a cytokine storm with this strain (1+ / 0-)
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      coigue

      Based on the reports of the dead mainly being 25-44 (the immune system goes haywire overreacting to the virus).  People with healthy immune systems are most prone to that.

      •  I saw a post somewhere else that said (0+ / 0-)

        Benadryl might help with a cytokine storm?  Is that correct?

        •  Cytokine storm wiki says: we don't know. (1+ / 0-)
          Recommended by:
          KimD

          Link

          Some types of arthritis medications are designed to reduce inflammation by inhibiting the tumor necrosis factor-alpha pathway to immune cell activation; these drugs are known as TNF-alpha blockers. One study[16] found that three different TNF-alpha blockers afforded a slight reduction in antibody presentation after vaccination against influenza in a group of immunocompromised patients, however it did not significantly affect patients' protective factor gained from inoculation. More research is necessary before any conclusions may be made regarding the efficacy of TNF-apha blockers at reducing the effects of a cytokine storm in hospitalized flu patients.

          2009: Year of the Donkey. Let's not screw it up.

          by Yamaneko2 on Sat Apr 25, 2009 at 01:08:46 PM PDT

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    •  It depends on the flu. (1+ / 0-)
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      coigue

      One aspect of this flu that is particularly worrying to people aged 25-49 is that this flu is particularly lethal to them.  

      The following is not diagnostic information.  It describes what happens during a truly terrible reaction to the flu.

      From the Wikipedia

      When the immune system is fighting pathogens, cytokines signal immune cells such as T-cells and macrophages to travel to the site of infection. In addition, cytokines activate those cells, stimulating them to produce more cytokines. Normally, this feedback loop is kept in check by the body. However, in some instances, the reaction becomes uncontrolled, and too many immune cells are activated in a single place. The precise reason for this is not entirely understood but may be caused by an exaggerated response when the immune system encounters a new and highly pathogenic invader. Cytokine storms have potential to do significant damage to body tissues and organs.[citation needed] If a cytokine storm occurs in the lungs, for example, fluids and immune cells such as macrophages may accumulate and eventually block off the airways, potentially resulting in death.[citation needed]

      In simpler terms, a body with a vigorous immune system overreacts to a novel pathogen.  In the case of the flu, lungs get blocked and the patient can die.

      2009: Year of the Donkey. Let's not screw it up.

      by Yamaneko2 on Sat Apr 25, 2009 at 01:06:47 PM PDT

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