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View Diary: Pique the Geek 20090621.  Drugs of Abuse III:  the Psychedelic Indoles (143 comments)

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  •  Toads and other stuff (4+ / 0-)
    Recommended by:
    Translator, C Barr, willb48, Larsstephens is a good website to read more about both the science and the effects of various plant and animal-based mind-altering drugs. It doesn't promote use as much as it promotes knowledge about the substances.

    That said, people also send in reports of their experiences with various drugs, both positive and negative. It's obvious that some responders are enthusiastic drug-takers, but quite often even those reports will caution others about certain compounds.

    Toad-sucking: what I learned recently is that the secretions from the toad need to be dried, and then maybe processed minimally. The resulting powdery stuff can then be smoked, which is the more efficient way to experience the effects of Bufo. Mind you, I haven't tried it, but I read the accounts at

    Good series, Doc!

    •  Thanks! (4+ / 0-)
      Recommended by:
      wenchacha, G2geek, C Barr, Larsstephens

      Yes that is a good site.

      I have intentionally been as neutral as possible in this series about promoting or discouraging the use of drugs, except when, in my professional opinion, I think that a specific drug poses a real danger of some sort.  Thus, I strongly condemned methamphetamine but supported the removal of all legal impediments to Cannabis.  I have tried to stay with the science.

      Warmest regards,


      Time for real health care reform, not just to patch the patches.

      by Translator on Sun Jun 28, 2009 at 08:14:15 PM PDT

      [ Parent ]

      •  Knowledge is good (4+ / 0-)
        Recommended by:
        G2geek, Translator, C Barr, Larsstephens

        What I like with your series, as well as erowid, is that science is at the source of the information. I think people would be better served to learn about the chemistry than a PSA like "This is your brain on drugs."

        I remember in college the great frustration that people would have with Organic Chemistry. It sounded terrible, and incredibly difficult. Now that I garden, I really wish I knew more about how it all works, especially with all the great scented herbs.

        •  I make occasional contributions to (4+ / 0-)

          the great post, What's for Dinner? that ek hornbeck runs here on Saturday evenings.  The last one by me was about why things brown and develop flavor when they are cooked at high temperatures.

          As for your herbs, did you know that spearmint and caraway seed are scented by exactly the same chemical, except, on a molecular level, one is "left handed" and the other one is "right handed"?  Please see a comment downthread.  Ask me questions.  They do not have to be on the topic in the main post.

          Warmest regards,


          Time for real health care reform, not just to patch the patches.

          by Translator on Sun Jun 28, 2009 at 08:53:16 PM PDT

          [ Parent ]

      •  sticking with the science, re. psychedelics... (2+ / 0-)
        Recommended by:
        Translator, Larsstephens

        ...suggests placing them on Schedule II, for use under the supervision of a  psychiatrist.  

        This would have the effect of making human subject research more accessible, which is my primary interest in this.  It would also enable clinical uses, for example DMT (in doses that are on the low side of average) as a psychotherapeutic adjunct that fits within the therapist's 50-minute hour.  

        Religious use could be handled by a requirement to have a psychiastrist present or immediately on-call, and a psychiatric nurse in attendance at any group sessions.  

        And of course, casual street use would still be illicit (though should be a citation offense), and the manufacturers and sellers to the street drug market could still be prosecuted.  

        Personally I think the greatest medical benefits from psychedelics will be found at much lower doses, even to the point of "homeopathic" doses (by which I mean, for example 1 to 5 micrograms of LSD taken daily, to prevent or reduce age-related cognitive decline).  (In that case, mis-use could be prevented by compounding the tablets with something that would induce nausea & vomiting if @ 25 or more tablets were taken at once.  Thus people would be discouraged from saving up a 3 month supply in order to take a trip.  If they wanted to take a trip, they would need to see their psychiatrist.)

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