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View Diary: Genome Redacted? (48 comments)

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  •  The thing about all of this is that (0+ / 0-)

    the generic issue of whether or not genes can be patented has been settled for many years.

    So, rightly or wrongly, there is now completely watertight precedent that genes can - for specifically-defined purposed - indeed be patented.  

    This basic fact was hashed out over a decade ago after (IIRC) Craig Ventner (perhaps the biggest asshole/publicity hound currently in science for whatever that's worth) was involved in efforts (based on NIH-funded research) to patent something like 20% of the human genes that had been sequenced up to that time (ca. 1990).  

    Of course, this attempt generated a huge uproar - leading to lively debate on topics such as "is patenting genes legal?" "is patenting genes ethical" etc etc.  Regardless of anyone's personal feelings on this issue, the basic concept that genes *can* be patented became well-established to the point that scholarly, retrospective-type books are now available on this topic.

    Thus, the ACLU has to know that their current efforts are entirely futile from a legal POV (in fact, if you look for their legal brief - available at one of the links supplied in the diary - it reads like it was written by a high school intern without a legal *or* scientific background.  Compared to one written by a $6000 an hour lawyer who actually has a scientific background (which is quite a rarity for a lawyer, hence the high cost) who are employed to write legal complaints when the complainant is actually serious about winning.

    Essentially, this whole things smacks of a sophomoric publicity stunt well below what you'd expect of a rather esteemed organization such as the ACLU.  I'm still scratching my head as to what the "real" motivation is . . . .

    •  The ACLU site (0+ / 0-)

      gives a different perspective than yours

      1. citing plantiffs who clearly have standing and scientific expertise, among them: Association For Molecular Pathology, American College Of Medical Genetics, American Society For Clinical Pathology, and College Of American Pathologists; and
      1. giving statements of support from what sound to me to be reputable organizations, including International Center for Technology Assessment, Council for Responsible Genetics, Center for Genetics and Society.

      But again, can you tell me if you have some grudge on this issue and/or this organization?

      •  Did you read their complaint? (1+ / 0-)
        Recommended by:

        available here

        It is simply just so much gibberish.

        For example - and I hope this will be an easy-to-understand example - claims 51 and 98 directly contradict each other

        Claim 51 claims that genes taken out of a cell are *exactly the same* as genes inside of a cell in all respects including their functions.

        Then Claim 98 (more correctly, btw) claims that genes interact with each other (and a vast array of other cellular components, btw) in complicated and undefined ways.  Well no, that can't be true if #51 is accurate in that genes are in every way identical inside a cell (where they can interact with other genes) and in isolated form outside the cell (where they cannot).

        You'd think that they'd at least be able to get somebody to proof read this document for internal consistency. . . .. right now, it's gotta be an embarrasment to the academic researchers they lined up to support them (in the earlier claims).

        •  I'm going to read the complaint now. n/t (0+ / 0-)
        •  I've looked at the complaint (0+ / 0-)

          and at Myriad Genetics' patent #7250497 "Large deletions in human BRCA1 gene and use thereof" in which the assignee claims, among many items, "1. An isolated nucleic acid comprising SEQ ID NO:6, and the complement thereof."

          I'm not competent to assess the patent and IANAL.  However, I can read, so I was struck by the passage in the ACLU complaint which states that Haig Kazazian, the Seymour Gray Professor of Molecular Medicine in Genetics in the Department of Genetics at the University of Pennsylvania School of Medicine

          "received a cease and desist letter from defendant Myriad as a result of work that was being done in the Genetic Diagnostic Laboratory of the Department of Genetics.  The laboratory directed by Dr. Kazazian was and is prohibited from doing routine screening for BRCA1 and BRCA2  genes for research or part of clinical practice without Myriad's permission as a direct result of the patents challenged by this action.

          This passage alone seems to indicate standing and puts to doubt your claim that the patents do not interfere with legitimate clinical and academic processes.

          So again, I'm wondering why you are so adamant in your attack on this issue.

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