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View Diary: Sequenced: The Human Genome - 10 Years Later (55 comments)

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  •  That devastating trial was at Penn, btw (0+ / 0-)

    It's something that is pretty much unspoken around campus.  Selective memory, I presume.  But at least the gene therapy folks have being stringently focusing on safety ever since.  And there have been some promising results since, specifically for inherited blindness.

    http://www.uphs.upenn.edu/...

    "Give me a lever long enough... and I shall move the world." - Archimedes

    by mconvente on Thu Feb 17, 2011 at 10:33:50 AM PST

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    •  Yes, but... (0+ / 0-)

      that's still generic therapy in that every effected individual gets the same treament.

      Personalizd medicine will be something like anti-sense RNAs that target base change derived resistance revealed by tiling array genomics of target genes.

      The regulatory structure is not designed to handle such small alteration in base pair changes as a developing therapeutic treatment. Under the current regime, each change would trigger a new submission or supplement.

      Based on my understanding of the matter.

      (-9,-9) pragmatic incrementalist :-P

      by Enterik on Thu Feb 17, 2011 at 11:28:27 AM PST

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