On her March 29, 2017 show, Samantha Bee explained the substitute amendment gambit Mitch McConnell may use to limit debate on the Senate health care bill, but from a very different direction.
Her example comes from Georgia and resulted in the unanimous votes in both the GA Senate and House to mandate that all rape kits be prosecuted, stopping them from being shelved indefinitely as they had been up till then:
https://youtu.be/s5eILKG5oSE