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As someone who is well aware of the inaccessibility of regular Big Pharma medicines in poor countries (Big Pharma are there to make money they are seldom Humanitarian and when they are they are at an insignificant levels).

I proposed accessible medicine for the common of mortal wherever they are and most of the time freely available.

I am not a qualify GP, I am just an Indigenous Medicinal Man that have done exhaustive studies for decennia’s on traditional medicines used in many cultures and I will therefore only promoted those that have managed to get duly corroborated by  Scientific Studies that have managed to be done via what most of the time are Approval Agencies control by the Big Pharma.  

Do no misunderstand me, I have worked with many patients that were relieved or cured by big Pharma medicines, but I have seen many being put six feet under and get more sick by these "duly pseudo scientifically authorized medicine".  The problem in most of the countries is that Scientific Institutions became through decennia’s simple subjects of Big Pharma Budget and Influences.

So Consumers Beware.

Snowy Owl

I have to add a <disclaimer tough, because <strong>sometimes Traditional or Alternatives medicines have been often used and promoted by the same greedy spirit of Big Pharma and have been presented on false or distorted pretentions or misleading information’s.

So again Consumers Beware from all those money makers, but do not disregard the pertinence of rightfull pretentions of some of their proposed medicines, but make your own opinion as responsable adults, to not become the baby spooned feed by greedy usurpators, whatever side they are.

Remember, if Big Pharma Medicines becomes non-available for some reasons, better remember these milleniums Natural medicines proven efficiency.

Curcumin

Curcumin Spice:
Research done in June 2006

Scientific Datas;

https://enzy.com/...
Curcumin inhibited the production of IL-8, MIP-1alpha, MCP-1, IL-1beta, and TNF-alpha by PMA- or LPS-stimulated monocytes and alveolar macrophages in a concentration- and a time-dependent manner. These results show that curcumin exhibits an inhibitory effect on the production of IL-8, MIP-1alpha, MCP-1, IL-1beta, and TNF-alpha by PMA- or LPS-stimulated monocytes and alveolar macrophages.

http://www.pdrhealth.com/...
The anti-inflammatory properties of the curcuminoids have been demonstrated in a number of in vitro and in some animal studies. These substances are widely used in India and Indonesia for various inflammatory conditions.

In vitro, curcumin inhibits the production of such pro-inflammatory cytokines as tumor necrosis factor-alpha (TNF-alpha), interleukin-1 beta (IL-1 beta) and interleukin-8, among other anti-inflammatory actions.

https://enzy.com/...

Turmeric has been attributed a number of medicinal properties in the traditional system of medicine and its internal as well local use has been advocated.

The major claims have been for use as antiseptic, cure for poisoning, eliminating body waste products, for dyspesia, respiratory disorders and cure for a number of skin diseases including promotion of wound healing.

Recent studies have confirmed some of the older claims and brought out several new useful properties.

Curcumin, curcuminoids and essential oils are the major active constituents. The main activities have been found to be anti-inflammatory, hepatoprotective, antimicrobial, wound healing, anticancer, antitumor and antiviral.

Different extracts of turmeric and also curcumin have been tried clinically in several diseased conditions with gratifying results.

Possible side effects/ adverse effects:

http://www.pdrhealth.com/...
CONTRAINDICATIONS

Curcuminoids should be avoided by those hypersensitive to any component of a curcuminoid-containing supplement.

Curcuminoids may stimulate bile production in some. The volatile oil of turmeric is thought to be responsible for the bile-stimulating activity of turmeric, but this has not been conclusively established.

Therefore, curcuminoids are contraindicated in those with bile duct obstructions and those with gallstones.

PRECAUTIONS

Pregnant women and nursing mothers should avoid curcuminoid supplemention.

Those with gastroesophogeal reflux disease (GERD) and those with a history of peptic ulcer disease should exercise caution in the use of curcuminoid supplements.

Curcuminoids may have antithrombotic activity in some. Therefore, those on warfarin or anti-platelet drugs should exercise caution in their use. Cancer patients should only use curcuminoid supplements under medical supervision.

Curcuminoid supplements must be taken with food. Curcuminoids may cause gastric irritation and ulceration if taken on an empty stomach.

ADVERSE REACTIONS

Adverse reactions of supplements principally comprised of curcuminoids are mainly gastrointestinal and include epigastric distress and nausea. There is one report of transient giddiness following curcuminoid ingestion. Abnormal liver tests have been reported in rats but not humans, and transient hypotension has been reported in dogs but, again, not in humans.

Curcuminoids may cause gastritis and peptic ulcer disease if taken without food.

INTERACTIONS WITH DRUGS

Chemotherapeutic agents: In animal studies, curcumin was found to enhance the antitumor effect of cisplatin against fibrosarcoma. It was also found to decrease the clastogenic effect of cisplatin. Also in animal studies, curcumin was found to decrease the nephrotoxicity due to doxorubicin and to decrease chromosomal aberrations due to bleomycin.

Anti-platelet drugs: Curcuminoids may enhance the action of anti-platelet drugs.

Warfarin: Curcuminoids may enhance the anticoagulant effect of warfarin.

Where to get it (food or supplement containing it, etc):

Curcumin is a constituent of the common kitchen spice Tumeric. Health food stores and vitamin suppliers should have the standardized supplement in tablet and capsule form.

http://www.pdrhealth.com/...

DOSAGE AND ADMINISTRATION
Curcuminoid supplements are available that contain curcumin at 70 to 75%, demethoxycurcumin at 15 to 20% and bisdemethoxycurcumin at about 3%. Doses used range from 500 to 4000 milligrams daily, and they are taken with meals.

Curcuminoids taken on an empty stomach may cause gastric distress.

IMPORTANT NOTE RE: BIOAVAILABILITY OF CURCUMIN

https://enzy.com/...
Medical Abstract Title:

Influence of Piperine on the Pharmacokinetics of Curcumin in Animals and Human Volunteers

(Piperine is found in black pepper. It is available in supplement form, Further information can be found here: http://www.pdrhealth.com/... It does have significnat interactions with some prescription drugs, so if you decide to use it, please read the PDR site first for possible interactions and other issues, and dosage levels.)

More to come as I am now reorganising my reasearch and collegues researches from now unused computers and hundreds of CD<s.</p>

I wish to express my Gratitude to Old time COllegues Shannon and LMonty and others with whom I have worked in Tandem since so many years at curevents.com and flutrackers.com

The Hindi (a language often spoken on the India subcontinent) name for Turmeric is Haldi.

Form the old fluwiki.com
INFORMATION DERIVED FROM: The Physician’s Desk Reference website

IMPORTANT NOTE: BIOAVAILABILITY OF CURCUMIN

Curcumin is poorly absorbed following ingestion in mice and rats. In these animals, 38 to 75% of an ingested dose is excreted directly in the faeces. Absorption appears to be better with food.

It has been demonstrated (Shoba G, Joy D, Joseph T, Majeed M, Rajendran R, Srinivas PS Planta Med. 1998; 64(4):353–356) that piperine improves absorption of curcumin. Piperine is found in black pepper. It is available in supplement form, Further information can be found here: http://www.pdrhealth.com/... It does have significant interactions with some prescription drugs, so if you decide to use it, please read the PDR site first for possible interactions and other issues, and dosage levels.)

From Med-owl.com

Curcumin is the compound that gives turmeric spice its bright yellow appearance. It has been used in herbal medicine for a variety of inflammatory conditions, including fever, arthritis, and psoriasis.  Curcumin not only blocks TNF, but it is an inhibitor of the MAPK p38 system.

At present, the Pubmed research database identifies 110 citations when searching for "MAPK curcumin" while the search phrase "TNF curcumin" returns 82 results.  Review of these articles makes it clear that curcumin holds great promise as an agent that may reduce the lethal effects of the avian flu cytokine storm.

Curcumin is quite inexpensive.

Absorption of curcumin is modest to poor, but can be increased when co-administered with piperine (a compound found in various species of pepper, including the black pepper found in most kitchens).  PMID: 9619120   Several commercial formulations of curcumin include piperine (sometimes called bioperine). Piperine itself inhibits TNF, IL-1, IL-6 and other inflammatory cytokines. PMID: 15531295

While it is best to store it at room temperature, it will not be completely inactivated under the un-refrigerated conditions that would destroy the potency of some expensive pharmaceutical TNF blockers.  Unlike the pharmaceutical TNF blockers, curcumin is associated with a reduced risk of many types of cancer.  In particular, lab studies have shown that curcumin induces apoptosis (programmed cell death) in several types of lymphoma.

For access to my research and many of my collegues here is the link
http://www.google.com/...

Snowy Owl

Originally posted to Snowy Owl on Sun May 24, 2009 at 04:59 AM PDT.

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Comment Preferences

  •  Hat Tip for the Wisdom of our Ancestors (6+ / 0-)

    Please read, I shook Hand with the devil of Romeo Dallaire. Thank you

    by Snowy Owl on Sun May 24, 2009 at 04:59:26 AM PDT

    •  Wisdom of our Ancestors? (3+ / 0-)
      Recommended by:
      TiaRachel, murrayewv, Arken

      In 1900, life expectancy in this country was 35-40 years.

      'Nuff said.

      •  Science, would you negate the universal facts (0+ / 0-)

        That our ancestors have succeed in reducing morbidity and mortality.

        Science, you must know a bit of History and know that if it was not of what you called Indians most of Europeans would have died of scorbut and..so many other infections and poisonnous afflictions.

        Denial of Truth in Medicines can cause a lot of sufferings.

        An off facts said

        Snowy

        Please read, I shook Hand with the devil of Romeo Dallaire. Thank you

        by Snowy Owl on Sun May 24, 2009 at 05:07:14 AM PDT

        [ Parent ]

      •  That was actually mostly due to (6+ / 0-)

        poor nutrition and sanitation.

        It doesn't really speak to the healing abilities of natural "drugs"  - which have definitely been oversold by charlatans in some cases, and almost always not used in a targeted way where their effects can be rigorously studied . . . but nonetheless do do have legitimate effects in many cases . . . . (think: aspirin!)

        •  Oops, posted too soon . . . (1+ / 0-)
          Recommended by:
          mattman

          I was going to add the ever popular "medical marijuana" to the list of natural pharmacologics. . . .

        •  I agree with you (3+ / 0-)
          Recommended by:
          TiaRachel, Roadbed Guy, Snowy Owl

          But the manner in which "natural drugs" are oversold by charlatans is what bothers me.  They always talk about the eutopian way in which are ancestors lived and how modern technology has made things worse (ignoring the reality of low life expectancies).  

          Certainly, you are right about aspirin, medical marijuana and others.  Even curcumin might be a good example (I know nothing about it, but am willing to learn)

          •  There's a peer-reviewed journal (4+ / 0-)

            called "Current Bioactive Compounds" - not really a top journal but respectable enough - that publishes many articles that aren't all that different from this diary (obviously, written & formatted in a more professional/scientific style of course . . .) that really make a strong case the Nature is full of "drugs" . . . .

            And sure, the problem is that there is a huge fuzzy area between having this knowledge, and actually using it in a rationale way to treat specific illnesses . . .

          •  There are many things in nature that are good for (0+ / 0-)

            and to call natural practitioners charlatans is really unfair.
            "Modern" medicine is good at surgery and giving drugs. And that's about it. They don't know how to cure becuase the premise is to practically kill a human being in order to kill what is wrong with them.
            There are ancient modalities like Chinese medicine and Ayurvedic medicine that have remarkable success in keeping people healthy and curing many illnesses (or preventing them).
            Our current model in the west is tops in surgery because this model was shaped by war. Every war has brought advances to surgery and critical care because in war you're more willing to try something new because you're just trying to save a life. And it has made today's surgical technique an amazing thing.
            But as to how to prevent and cure modern diseases, they fail completely.
            I'd love to see the western model open its mind to study why certain foods, or other medical ways, can affect health. But then, Big Pharma doesn't want people to use natural ways becuase they can't make a buck off it.

            Electing conservatives is like hiring a carpenter who thinks hammers are evil.

            by MA Liberal on Sun May 24, 2009 at 07:40:44 AM PDT

            [ Parent ]

  •  Drug companies have patented all those drugs (0+ / 0-)

    and may stand to make a huge profit in a few years from them. They are in like Flynn with some top politicos on this.

    They claim that there is no "incentive" to research on "almost free" supplements so they want to make them prescription drugs to incentivize new research (most research has already been done) and "prevent their abuse".

    Google Codex..

    Also, some folk are concerned that people are living too long.

    To get fish oil, or more than the RDA in one pill of Vitamin B6, you might have to pay a $20 copay but the drug company who owns the use patent gets $200

    Only Single Payer- not any "optionals" will allow doctors to practice medicine, not simply cost control.

    by Andiamo on Sun May 24, 2009 at 05:12:51 AM PDT

    •  In 1934, life expectancy was 65 (0+ / 0-)

      thats how they arrived at the age for Social Security

      Only Single Payer- not any "optionals" will allow doctors to practice medicine, not simply cost control.

      by Andiamo on Sun May 24, 2009 at 05:14:32 AM PDT

      [ Parent ]

      •  Correct. (1+ / 0-)
        Recommended by:
        Arken

        And in the 1890's, it was 44.  The big increase had nothing to do with Big Pharma, but was due to improved sanitation.

        •  Again in 1890 there was the Rusian Grippe a very (0+ / 0-)

          Bad pandemic, a world wide one, even in the town near ya.

          Snowy

          Please read, I shook Hand with the devil of Romeo Dallaire. Thank you

          by Snowy Owl on Sun May 24, 2009 at 05:23:31 AM PDT

          [ Parent ]

        •  Well, since you admit that sanitation (2+ / 0-)
          Recommended by:
          mattman, Snowy Owl

          was the key factor, why the slam against "the wisdom of our fathers" upthread?

          •  "Our fathers" (2+ / 0-)
            Recommended by:
            murrayewv, Snowy Owl

            Didn't understand basic sanitation. I wouldn't call that especially wise.

            •  Your Right, they should have listen the Mother Cl (0+ / 0-)

              The Mother Clan, btw in all Cultures that I have done Immersion in for few years, all experience Women where yelling in the desert that sanitation was a must, (Women that where still up, not those depressed and discouraged and then submitted to mysogynists Cultures.

              Only Woman Bleed, they discover rapidly the necessity of good hygiene.

              Miladies, do not yell at us, anyway as you know, many of us are deafth, but about hand washing and how to sneeze and cough in public, in these days and in months ahead it is very important, no Public Health Interventionnists disagree an iota on this.

              Here is a short video of Hand Washing (Do not forget the Nails, they are probably the best transmitters via the Hand) and  How to behave when you Dare to Care about others in Public when you sneeze or cough.

              Both and other videos are short and sweet via Here.

              Snowy

              Please read, I shook Hand with the devil of Romeo Dallaire. Thank you

              by Snowy Owl on Sun May 24, 2009 at 06:20:51 AM PDT

              [ Parent ]

            •  Maybe not yours did not . . mine did just fine. (1+ / 0-)
              Recommended by:
              Snowy Owl

              Sanitation has been "understood" since ancient Egypt, the Romans took it to high art forms in fact . . . (in addition to the practicalities involved)

              In practice, the resources were not always in place for proper execution of the concept, however.

              •  Right Roadby Guy (0+ / 0-)

                But because all those Aristocrats believed the lived in Ivory Towers and decided to ignored to educate and give a hand to those who where feeding them, Decimating Pandemics occured, and they seems to ignore Status in Society.

                Snowy

                Please read, I shook Hand with the devil of Romeo Dallaire. Thank you

                by Snowy Owl on Sun May 24, 2009 at 06:35:23 AM PDT

                [ Parent ]

        •  You have to give some credit (2+ / 0-)
          Recommended by:
          murrayewv, Snowy Owl

          to antibiotics and vaccines.

          "There -- it's -- you know, one of the hardest parts of my job is to connect Iraq to the war on terror." --GWB

          by denise b on Sun May 24, 2009 at 07:26:32 PM PDT

          [ Parent ]

          •  no s/he doesn't..... (1+ / 1-)
            Recommended by:
            SnowCountry
            Hidden by:
            Snowy Owl

            folks like this  want to return us to some sort of independent ideal that never actually occured.  They never give credit to sanitation, sufficient calories, vaccines, endless war.  That is why Africa is still in the 19th century and other places with similar climates make progress.  The wisdom of Native Americans is held up as fabulous.  The traveling snake oil salesmen always said it was an herbal cure from native peoples.  And it was whiskey and opium, which actually helped with the diarrhea from waterborne illnesses like typhoid and typhus.  Native Americans were decimated by measles but got us back with syphilis.  

            You shall know the truth, and the truth shall make you mad. Aldous Huxley

            by murrayewv on Mon May 25, 2009 at 04:30:34 AM PDT

            [ Parent ]

      •  Wrong, Workers Expected Years of Retirement (5+ / 0-)
        Recommended by:
        TiaRachel, ybruti, denise b, Roadbed Guy, OHdog

        The average was dragged down by infant and childhood mortality, and infectious disease through life.

        It was just discussed here a few days ago, I believe the figure was 15 years' average retirement expected.

        We are called to speak for the weak, for the voiceless, for victims of our nation and for those it calls enemy.... --ML King "Beyond Vietnam"

        by Gooserock on Sun May 24, 2009 at 05:26:44 AM PDT

        [ Parent ]

        •  A key piece of information that should be (1+ / 0-)
          Recommended by:
          billlaurelMD

          included when "life expectancy" numbers are bandied about is when the determination is being made.

          For example, if life expectancy at birth for males in Paraguay is 73, it does not follow that life expectancy for a group of 73 year olds in this cohort is zero.

      •  Stress is the biggest cause of death ... today (1+ / 0-)
        Recommended by:
        Snowy Owl

        and ever.  Stress because of mortgages, the economy, healthcare, OR other cave men clubbing you to death ....

        With that profound statement, I close out my session today.  My 30th comment without a reply.  I'm out of here.

        •  I thought it was heart disease. n/t (1+ / 0-)
          Recommended by:
          murrayewv
          •  Please, not funny for those who have it (0+ / 0-)

            Please read, I shook Hand with the devil of Romeo Dallaire. Thank you

            by Snowy Owl on Sun May 24, 2009 at 06:21:30 AM PDT

            [ Parent ]

            •  I wasn't joking. n/t (1+ / 0-)
              Recommended by:
              murrayewv
              •  I know, Europeans called (0+ / 0-)

                Our Great Turtle the Bitterness (America) Hemisphere.

                See the Historical Impacts on so many Fields of our Common History to us all.

                Snowy

                Please read, I shook Hand with the devil of Romeo Dallaire. Thank you

                by Snowy Owl on Sun May 24, 2009 at 06:25:57 AM PDT

                [ Parent ]

              •  I think stress causes heart disease. (2+ / 0-)
                Recommended by:
                Arken, Snowy Owl

                But, I meant this partially tongue-in-cheek to point out that (like other comments) there is reason to believe in modern medicine and reasons to shun it.  I could go on an on.  I am so torn between taking my beta blockers and trying to find time to meditate.  But, my point, in reality is that there is a cult of belief out there that natural is good and man-made is bad.

                Oh, and, yes I think heart disease is number one.  My own husband died of it three years and seven months ago .. at the age of 47.  Wish he had had a warning shot.  And, wish everyone one would choose a balance between healthy attitude and going to to doctor.

                •  Beta nad Meditation (0+ / 0-)

                  From Non Totally Medical Group, it is recognised that very Tiny reduction in quantities of Beta-innibitors and 15 minutes after intake a 15 minutes of Deep Breathing (good first immerdion in meditation state (good alpha brain waves EEG corroborated), is the Trail of Wheel Being without beta-innibitors.

                  Snowy

                  Please read, I shook Hand with the devil of Romeo Dallaire. Thank you

                  by Snowy Owl on Sun May 24, 2009 at 06:51:28 AM PDT

                  [ Parent ]

        •  Psst, wait (0+ / 0-)

          You Spoke Truth AllieDoc, you are right.

          Maybe because I meditate and that I know and proud of doing my best, so this killer stress, and Miladies, without being mysogynes (that I abbhore btw), that buldozer (driller) stress affect us (men) more than women.

          It it us often unexpetdely, and when it occur suddenly, One's must immediatly do Deep Breathing to stimulate the Vagus Nerve, provide a better intake of oxigen, granthing seconds to get the pulse down, so yes when it occur in Man, do not freak out about cardiac attack, Remember DEEP BREATHING.

          Keep that pace slowly, communicate the malaise and your need for calm, go to the hospital or see ASAP your doc.

          But Ii work.

          Reh, Deep Breathing

          Snowy Owl

          Please read, I shook Hand with the devil of Romeo Dallaire. Thank you

          by Snowy Owl on Sun May 24, 2009 at 06:09:20 AM PDT

          [ Parent ]

  •  What the heck is (2+ / 0-)
    Recommended by:
    TiaRachel, Snowy Owl

    IL-8, MIP-1alpha, MCP-1, IL-1beta, and TNF-alpha by PMA- or LPS-stimulated monocytes

    Sounds like a chemical.

    Actually, I was thinking of genetically engineering curcumin production.  I should do it.

    •  Well all plants have chemical components (0+ / 0-)

      See,

      That is why I do not disregard Scientific and Medical Progress, they now corroborate even genetically common Ancestral Instinctive or maybe Historically Deep Knowledge.

      Snowy

      Please read, I shook Hand with the devil of Romeo Dallaire. Thank you

      by Snowy Owl on Sun May 24, 2009 at 06:28:47 AM PDT

      [ Parent ]

  •  Please edit the diary. (3+ / 0-)
    Recommended by:
    TiaRachel, murrayewv, wondering if
    1. Most of the links don't work ("page not found," etc.).
    1. You're still not following the rules in the dKos FAQ re  how much copyrighted material may be quoted. The fact that you have previously gathered copyrighted material and quoted more of it than dKos permits doesn't make the result "[your] research."
    1. . . . A reasonable rule-of-thumb is that copying three paragraphs from a normal-length news article or editorial is acceptable. (This, however, is not a safe-harbor. If even three paragraphs seems like "too much," then copy less or nothing at all.) . . .
    1. You're not using blockquotes to indicate  material that's being quoted:
    1. . . . [U]se the blockquote tags to set off the copied material so that your writing is distinct from the material you are copying.

    Writing Diaries/Diary guidelines

  •  Curcumin is being studied for its positive (2+ / 0-)
    Recommended by:
    Snowy Owl, CKendall

    effects on the brain and as a possible Alzheimer's preventative. Researchers were intrigued that there was such a low incidence of dementia/Alzheimer's in India. But the Indians eat a lot of curry which contains 9din! ding! ding!) turmeric (curcumin).
    What today's medical practitioners often fail to realize is that nature gave us everything we need to stay healthy. Most drugs started by taking advantage of certain plants properties. But you can't get rich on nature, so Big Pharma prefers to synthesize it and make their profits. of course, they kill thousands every year with their stuff.
    As Hipocrates (the father of medicine) said:

    "Let your food be your medicine, and your medicine be your food"

    After all, is a lot more about food than just satisfying hunger.

    Electing conservatives is like hiring a carpenter who thinks hammers are evil.

    by MA Liberal on Sun May 24, 2009 at 07:34:08 AM PDT

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