A substantial number of Daily Kos diaries have been written on Lyme Disease. Many have discussed the debilitating aftermath to this infection whether or not it was correctly diagnosed in the first place. Other diaries have been on the medical/political circus surrounding the physicians that treat the lingering symptoms vs those that think it is malpractice to treat an unproven chronic infection. Now a very interesting study is going to reinvigorate the entire controversy.
Plos Pathogen is an on line journal that published in its May edition an article titled "Lymphoadenopathy during Lyme Borreliosis Is Caused by Spirochete Migration-Induced Specific B Cell Activation". Although I am not an expert on the causative organism of Lyme Disease, Borrelia burgdorferi, it appears that in an animal model of the disease the bacteria hides inside lymph nodes. This hidden mode makes it difficult to find the persistent infection and its presence in the lymph node interacting with all the immune cells there may explain many of the post infection symptoms seen in the often dismissed "chronic Lyme Disease". If you'd like to review the reference yourself "Tunev SS, Hastey CJ, Hodzic E, Feng S, Barthold SW, et al. 2011 Lymphoadenopathy during Lyme Borreliosis Is Caused by Spirochete Migration-Induced Specific B Cell Activation. PLoS Pathog 7(5): e1002066. doi:10.1371/journal.ppat.1002066