No, not when is lips are moving. Although one wonders whether we are approaching that level, given the recent revelations about his "prowess" as a marathon runner.
This is actually for real.
My 84-year-old Mom, a solid liberal and a very smart woman, noticed a certain behavior during Paul Ryan's speech that is a dead giveaway.
I didn't watch the speech, but this sounds plausible. What she noticed was that every time he prepares to lie, he ducks his chin and opens his eyes wide, looks right at you, and out comes the lie. She characterized it as "just like a little boy getting ready to tell mommy that he didn't do it."
Take a look at clips of his speech and see if you see the same thing, and share the results of your observations in the comments, I'll be curious to see if you also notice the pattern.