Possible Type 1 Diabetes Cure

We have seen many trials of islet cell transplant techniques for Type 1 diabetes, with various methods of protecting them from the immune system. Here is another, an improved anti-rejection drug being tested for a wide range of auto-immune diseases and transplants.

Experimental diabetes treatment helps Chicago woman go off insulin

Doctors have been doing islet cell transplants for years now, but the University of Chicago is the first hospital to use a certain anti-rejection drug called tegoprubart. Doctors say it’s not as toxic as other anti-rejection drugs and has little or no side effects. That’s the difference here.

Patients who have been passing out with low glucose will have a much easier time taking an effective anti-rejection drug than trying to titrate insulin injections.

Eledon Pharmaceuticals Announces Positive Initial Data from Subjects with Type 1 Diabetes Treated with Tegoprubart as Part of an Immunosuppression Regimen Following Islet Transplantation in Investigator-Initiated Trial at UChicago Medicine

WCN23-0454 TEGOPRUBART FOR THE PREVENTION OF REJECTION IN KIDNEY TRANSPLANT RECIPIENTS: A SNAPSHOT OF EMERGING DATA FROM AN ONGOING TRIAL

Safety and tolerability of tegoprubart in patients with amyotrophic lateral sclerosis: A Phase 2A clinical trial

Personal Note

It’s good to be back with you, now that election season is over and resistance season has begun. See the daily Good News Roundups for regular reporting on Republican internal chaos and infighting.

My neuropathy gets a bit better with exercise and a bit worse when my blood sugar spikes, varying every day. I am looking forward to the day when one of the agents that we see in trials turns out to be safe and effective enough to get FDA approval, assuming that RFKjr doesn’t get to wreck the FDA, CDC, HHS, and all of our other health agencies. Our best hope for that seems to be chaos and infighting among the Trumpists and in Congress.

I’ll let you know.