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Salutations to all,

Friday in the Medical Field (among others) is the day of Major News and I will keep the pace until this diary sinks into the Undergrounds.

Today, as usual, I will make a Wrap-Up on Swine Flu, that is H1N1 from around the World.  I will post and start to comment on Updates expected today from International and National Medical Institutions.

I will start to post comments on duly corroborated datas about anti-virals that are accessible for all budget and over the counter.

NOTA: I am not a Physician, I am just a Traditional OjibWay Medicine Men of the Iroquois Nation (North-East of North-America), your best resource for Health Care Advice still is your family doctors. My comments, altough validated by institutions are for your information only and does not constitute a Medical advice.  
Thank you,

Achak
Snowy Owl

Due to the potential gravity of the situation, The New England Journal of Medicine (N Engl J Med or NEJM) is an English-language peer-reviewed medical journal published by the Massachusetts Medical Society. It is one of the most popular and widely-read peer-reviewed general medical journals in the world. It is also the oldest continuously published medical journal in the world., yesterday they  published on their website freely accessible Medical Informations and a number of papers on the recent swine flu outbreak.

First Thing First
With those whom we wish we wont have to go see.

New England Journal of Medicine
May 7, 2009
Published at www.nejm.org May 7, 2009 (10.1056/NEJMe0903992)
H1N1 Influenza A Disease — Information for Health Professionals

Although the exact sequence of events is uncertain, by the third week of April it was established that the illness resulted from a triple recombination of human, avian, and swine influenza viruses; the virus has been found to be H1N1.

This virologic analysis allowed for the development of a polymerase-chain-reaction (PCR) test to determine whether, in any given person, illness with the protean manifestations of cough, fever, sore throat, diarrhea, and nausea could be confirmed as a case.

Armed with this critical tool, clinicians and epidemiologists are able to make case assignments to define and track the outbreak and to determine disease severity.

Health authorities from around the world formulated plans for monitoring and controlling this outbreak.

On May 7, 2009, just about a month after the first case of this new H1N1 influenza was recognized, we are publishing articles providing background information about novel recombinant forms of H1N1 influenza causing human disease in the United States and a summary of the outbreak cases reported in the United States as of May 6.

Our goal in publishing these articles is to provide clinical descriptions of patients with the condition so that health professionals can use this information in making the difficult decision about whether an individual patient has a suspected case.

This decision will depend on the presence of typical, but unfortunately variable and nonspecific, symptoms; an epidemiologic link to other known suspected or established cases (though this may become less useful as the infection becomes widespread throughout the population); and, where appropriate, a positive identification of the H1N1 virus by the PCR test (see video for the correct method of obtaining a nasal sample).

Making informed decisions in thse beginning Time is sometimes confusing and even conflicting so yes itis important IMHO opinion.
Achak

First, credible suspected cases should trigger public health measures such as contact tracing and quarantine — which will benefit the community — and consideration for treatment with neuraminidase inhibitors, which will potentially benefit the individual patient.

Obviously, if we assign suspected-case status to more people than belong in this category, we alarm the public and create hardship for many who will turn out to be influenza-negative.

If we miss suspected cases and the affected people circulate in the community, the illness will spread more rapidly.

Finding the Right Balance in Raising Awareness, in Diffusing Corroborated Informations as Humanitarians is the Challenge of Our Life.

Finding Equipoise will be difficult, but our efforts should be guided by the informations as they are diffuse in a Democratic Humanitarian Movement.

Achak

The ability to clearly define a confirmed case will also allow for a careful assessment of the associated illness and its severity.

We now have important tools with which to fight this outbreak:
a clear case definition, an aware health care system, and an informed public. We await the availability of a vaccine, which will require several months to prepare.

Although it has been just over a month since the first cases were identified, it seems unlikely that this outbreak will lead to widespread, severe illness and deaths.

However, this may be just the first wave, and we will carefully monitor this outbreak.

To help in this process,
we have established
the H1N1 Influenza Center at NEJM.org, which is open and available to all.

We have and will post original research and other articles, as well as Journal Watch summary and commentary on important articles that may appear elsewhere.

We have also posted historical pieces from our archive on the "swine flu" epidemic of the 1970s and the 1918 influenza epidemic.

The H1N1 Influenza Center
we will also have links to the most up-to-date news on the outbreak, including material from sources such as the World Health Organization and the Centers for Disease Control and Prevention.

One highlight is an interactive map from HealthMap showing the location of confirmed and suspected cases of H1N1 influenza in the United States and around the world.

This map, which uses information from many different sources, will be updated regularly.

We hope that the H1N1 Influenza Center will be of value to health professionals as they participate in the control of this outbreak.

In addition, we will continue to follow this problem after the current outbreak subsides, since illness may recur in the Southern Hemisphere during the coming winter or again in the Northern Hemisphere when the traditional influenza season returns.

Snowy Owl

Originally posted to Snowy Owl on Fri May 08, 2009 at 06:09 AM PDT.

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Comment Preferences

  •  Tip/Jar for the tenacity of so many (10+ / 0-)

    In trouble to be troubled Is to have your trouble doubled. Daniel Defoe No "panic" in "pandemic."

    by Snowy Owl on Fri May 08, 2009 at 06:10:16 AM PDT

  •  Does this current strand (H1N1) (1+ / 0-)
    Recommended by:
    Snowy Owl

    have elements of bird flu in it already?

    Ann Compton to President Obama at next presser: "Is it true that once you go black, you can never go back?" Obama: "WTF?"

    by dlh77489 on Fri May 08, 2009 at 06:31:06 AM PDT

  •  Top flu expert warns of a swine flu-bird flu mix (1+ / 0-)
    Recommended by:
    Lisa Lockwood

    Hat Tip to PabloMorgan at Flutrackers

    Top flu expert warns of a swine flu-bird flu mix

    By MARGIE MASON

    MEXICO CITY (AP)

    Bird flu kills more than 60 percent of its human victims, but doesn't easily pass from person to person. Swine flu can be spread with a sneeze or handshake, but kills only a small fraction of the people it infects.

    So what happens if they mix?

    This is the scenario that has some scientists worried: The two viruses meet — possibly in Asia, where bird flu is endemic — and combine into a new bug that is both highly contagious and lethal and can spread around the world.

    Scientists are unsure how likely this possibility is, but note that the new swine flu strain — a never-before-seen mixture of pig, human and bird viruses — has shown itself to be especially adept at snatching evolutionarily advantageous genetic material from other flu viruses.

    "This particular virus seems to have this unique ability to pick up other genes," said leading virologist Dr. Robert Webster, whose team discovered an ancestor of the current flu virus at a North Carolina pig farm in 1998.

    "Do not drop the ball in monitoring H5N1," WHO Director-General Margaret Chan told a meeting of Asia's top health officials in Bangkok on Friday by video link. "We have no idea how H5N1 will behave under the pressure of a pandemic."

    Experts have long feared that bird flu could mutate into a form that spreads easily among people. The past three flu pandemics — the 1918 Spanish flu, the 1957-58 Asian flu and the Hong Kong flu of 1968-69 — were all linked to birds, though some scientists believe pigs also played a role in 1918.

    Webster, who works at St. Jude's Children's Research Hospital in Memphis, Tenn., said bird flu should be a worry now. Bird flu is endemic in parts of Asia and Africa, and cases of swine flu have already been confirmed in South Korea and Hong Kong.

    "My great worry is that when this H1N1 virus gets into the epicenters for H5N1 in Indonesia, Egypt and China, we may have real problems," he told The Associated Press. "We have to watch what's going on very diligently now."

    Spokesman Dave Daigle said he could not comment specifically on how concerned the U.S. Centers for Disease Control and Prevention is about the scenario Webster describes, or what it is doing to study such a possibility.

    Malik Peiris, a flu expert at Hong Kong University, said the more immediate worry is that swine flu will mix with regular flu viruses, as flu season begins in the Southern Hemisphere. It is unclear what such a combination would produce.

    But he said there are indications that scenario is possible. Peiris noted that the swine flu virus jumped from a farmworker in Canada and infected about 220 pigs. The worker and the pigs recovered, but the incident showed how easily the virus can leap to a different species.

    "It will get passed back to pigs and then probably go from pigs to humans," Peiris said. "So there would be opportunities for further reassortments to occur with viruses in pigs."

    Snowy Owl

    In trouble to be troubled Is to have your trouble doubled. Daniel Defoe No "panic" in "pandemic."

    by Snowy Owl on Fri May 08, 2009 at 06:31:17 AM PDT

  •  Snowy Owl, as inappropriate as this might seem (0+ / 0-)

    in this diary can you one day do a diary on the Iriquois Nation. Check out my sig line. I am fascinated as to the origins of this seven generations quote.
    BTW I picked it up from the 11th Hour and from Van Jones book The Green collar economy.

    "In our every deliberation, we must consider the impact of our decisions on the next seven generations." Law of the Iroquois Confederacy

    by Unenergy on Fri May 08, 2009 at 06:31:58 AM PDT

    •  Dear Unenergy, dear Flint Brother (2+ / 0-)
      Recommended by:
      Lisa Lockwood, Unenergy

      I have been monitering thing at Night Owl Time and because of the repercussions of our actions NOW it will indeed, as we know, impact the nest seven Generations.

      Last time (1918), one, just one good American docotor dared to come into the reserve to tell us to stop morning our dying ones besides them for the Night because, with what we have and knew then, it would killed all of us.  You know how many Villages got decimated in 1918 -1920.

      I decided six years ago to go ahead and democratised the Knowledge of in Incoming Diseases, Resources, Know-How and Daring to Care.

      Snowy

      In trouble to be troubled Is to have your trouble doubled. Daniel Defoe No "panic" in "pandemic."

      by Snowy Owl on Fri May 08, 2009 at 06:41:12 AM PDT

      [ Parent ]

  •  Swine-Origin Influenza A (H1N1) and HIV (0+ / 0-)

    Swine-Origin Influenza A (H1N1) and HIV

    The CDC offers guidance for HIV-infected patients potentially exposed to swine flu.

    Many HIV-infected individuals and their providers are understandably concerned about the risks of H1N1 infection.

    On April 30, the CDC issued interim guidance on this particular issue.

    At this point, sufficient data are not available to determine whether HIV-infected individuals are at increased risk for complications of H1N1 infection.

    Dr. Sierra-Madero has been actively calling HIV providers in Mexico City and has yet to hear of any cases of influenza A (H1N1) among HIV-infected patients during the current outbreak.

    Limited evidence from seasonal influenza studies indicates that influenza may be no more severe for most HIV-infected individuals than for healthy, HIV-negative individuals.

    Nevertheless, clinicians should be aware that HIV-infected individuals who acquire H1N1 infection — especially those with AIDS or low CD4-cell counts — may be at increased risk for more severe disease and complications.

    In addition, they may be at increased risk for secondary bacterial infections, including pneumonia

    The CDC’s core recommendations for treatment and chemoprophylaxis in HIV-infected adults are the same as those for other populations at increased risk for complications from influenza:

    HIV-infected adults and adolescents who meet current case definitions for confirmed, probable, or suspected H1N1 infection should receive empiric antiviral treatment.

    HIV-infected adults and adolescents who are close contacts of persons with probable or confirmed H1N1 infection should receive antiviral chemoprophylaxis.

    HIV-infected adolescents and adults who are household contacts of a suspected case can consider antiviral chemoprophylaxis.

    There are no known contraindications for coadministration of oseltamivir or zanamivir with currently available antiretroviral medications.

    Comment: Clinicians should keep in mind the possibility of prolonged drug-resistant influenza virus infection occurring in immunosupressed individuals with lymphocytopenia (J Infect Dis 2009;199:1435).

    Although a reasonable estimate of the effectiveness of influenza vaccination for HIV-infected individuals cannot be made conclusively, a meta-analysis (HIV Med 2008; 9:57) suggests that it is around 50%; thus, it is prudent to immunize all HIV-infected persons against seasonal influenza each year.

    The ACIP recommends routine influenza vaccination for HIV-infected individuals; however, recent data indicate that vaccination rates remain low (J Infect Dis 2007; 196:339). Ongoing general information on the H1N1 epidemic can be found at http://www.pandemicflu.gov.

    Snowy Owl

    In trouble to be troubled Is to have your trouble doubled. Daniel Defoe No "panic" in "pandemic."

    by Snowy Owl on Fri May 08, 2009 at 07:21:14 AM PDT

  •  When pigs fly.... (0+ / 0-)

    We will have Avian Swine Flu

    Coming Soon -- to an Internet connection near you: Armisticeproject.org

    by FischFry on Fri May 08, 2009 at 07:23:11 AM PDT

  •  Predicted, Observed Times of Influenza 1968/9 (1+ / 0-)
    Recommended by:
    bronte17

    Predicted and Observed Times of Influenza Activity and Epidemic Peaks in 1968/9

    (A) Predicted combined incidence using baseline model assumptions (bold lines show mean incidence).

    (B) Observed and predicted times in individual cities.

    Peak times from individual simulation runs and mean peak times with 1968/9 data are shown as blue and white dots, respectively. Mean peak times that would have occurred with 2002 travel patterns are shown as yellow dots. Predictions are based on 100 simulation runs. Influenza activity was defined as at least one new symptomatic case per 100,000 people in a given week.

    Despite large variation in the timing of predicted epidemic peaks in individual cities between simulation runs, the overall course of the pandemic was quite predictable (Figure 3A),

    Although there was markedly more between-run variability in the tropics and the south than in the north.

    The roughly ten-fold increase in air traffic since 1968 causes epidemics in most cities to peak between 1 and 2 months earlier than they would have done in 1968 (in some southern hemisphere cities the epidemic peaks 1 y earlier) and substantially reduces variation between simulation runs (Figure 3B).

    The model reproduced another interesting aspect of influenza epidemiology: the tendency for peak periods of influenza activity in the tropics to shift with latitude, so that in the northern tropics they are closer to countries north of the tropics, while the southern tropics tend to be more closely aligned with countries south of the tropics [24].

    This occurs despite the fact that the model has no explicit assumptions about seasonality for cities in the tropics; the behaviour arises only as a result of the strength of transport connections between different regions.

    It is also notable that the pandemic starts early enough to allow some probability of influenza activity in the south during the end of the flu season in 1968.

    Despite this, predicted epidemic peaks (the weeks with the greatest number of reported cases in each location) still occur in 1969 in the south.

    When we used the model to evaluate interventions using contemporary air travel and demographic data, we found that travel restrictions to and from affected cities would slow epidemic spread, but unless almost all air travel from affected cities (i.e., greater than 99%) was suspended, the potential for delaying the pandemic was limited (Figures 4–6 and Table 1).

    Even when 99.9% of air traffic was suspended, most cities had a low probability of ultimately escaping the pandemic (Figure 4), and delays large enough to be of clinical significance (6 months or more) were common only if interventions were made after the first few cases (Figure 5).

    Interventions that reduced transmission could typically lead to more pronounced delays (Figures 5 and 6 and Table 1), although only when Rt was reduced to slightly above one were these sufficient to delay epidemics until the next influenza season.

    These findings were not highly sensitive to assumptions about initial susceptibility and transmissibility.

    Snowy Owl

    In trouble to be troubled Is to have your trouble doubled. Daniel Defoe No "panic" in "pandemic."

    by Snowy Owl on Fri May 08, 2009 at 07:28:08 AM PDT

  •  In vivo anti-influenza virus activity of plant fl (1+ / 0-)
    Recommended by:
    bronte17

    In vivo anti-influenza virus activity of plant flavonoids possessing inhibitory activity for influenza virus sialidase.

    Sincere thanks to LMonty, a RN Old Timer in Flu Board, she exceptionnally conjugate alternatives medicine and pharmaceutical medicines, she has all my respect.
    Snowy

    The flavone showed significant anti-influenza virus activity in vitro similar to isoscutellarein-8-methylether (F36) (Nagai, T., Miyaichi, Y., Tomimori, T., Suzuki, Y. and Yamada H., 1990, Chem. Pharm. Bull. 38, 1329-1332), and more potent virucidal activity in ovo than F36.

    However, F36 completely prevented proliferation of mouse-adapted influenza virus A/PR/8/34 in mouse lung by the intranasal (0.5 mg/kg) and intraperitoneal (4 mg/kg) administrations, and it was more potent than the known anti-influenza virus substance, amantadine.

    Intranasal administration of F36 (0.5 mg/kg) also protected mice against a lethal influenza virus A/PR/8/34 infection.

    Isoscutellarein significantly inhibited lung virus proliferation when administered intranasally or orally to mice.

    F36 and isoscutellarein showed negligible toxic effect against mice.

    These results suggested that flavones, which have potent influenza virus sialidase inhibitory activity, have anti-influenza virus activity in vivo.

    Snowy

    In trouble to be troubled Is to have your trouble doubled. Daniel Defoe No "panic" in "pandemic."

    by Snowy Owl on Fri May 08, 2009 at 07:31:56 AM PDT

  •  Antioxidant-Polyphenols in fruits inhibits flu vi (1+ / 0-)
    Recommended by:
    bronte17

    Antioxidant-Polyphenols in fruits inhibits flu virus

    Chemical in grapes inhibits flu virus

    May 31, 2005 (CIDRAP News)

    Resveratrol, a chemical found in grapes and other fruits, inhibits the reproduction of influenza viruses in cell culture and mice, according to a recent report in the Journal of Infectious Diseases.

    Rather than directly attacking the flu virus itself, resveratrol seems to block host-cell functions that are essential for viral replication, says the report by Anna T. Palamara and colleagues at the University of Rome. They write that the substance holds promise as a possible weapon against flu.

    Resveratrol is an antioxidant that is found in at least 72 plant species and is known to help protect the heart and nervous system and help prevent cancer, says the report.

    In an initial cell-culture experiment, treatment with resveratrol at 20 mcg/mL reduced flu virus replication 90%, and treatment with 40 mcg/mL blocked replication completely.

    However, because the higher concentration damaged the cells, the lower concentration was used in further tests.

    Treatment was most effective—reducing viral growth 87.5%—when treatment began 3 hours after virus exposure. Effects were lower but still significant when treatment began 6 hours after infection, and treatment had no significant benefit if delayed until 9 hours after infection.

    Given these and other findings, the researchers concluded that resveratrol interferes with the manufacture of proteins made late in the viral replication process, such as hemagglutinin, and limits the transport of viral ribonucleoproteins from the cell nucleus to the cytoplasm.

    The authors also determined that the molecular mechanism for resveratrol's effects has to do with the inhibition of protein kinase C activity and its dependent pathways.

    "We have shown that RV [resveratrol], a natural polyphenol whose concentration in red wine is 1.5-3.0 mg/L, can inhibit the in vitro and in vivo replication of influenza A virus without producing any significant toxicity," the article states.

    The apparent ability of resveratrol to block host-cell functions that flu viruses rely on offers important advantages, the researchers say. Compared with existing anti-flu drugs, resveratrol would be less likely to induce resistance by flu viruses, and it would probably be effective for all types and strains of flu virus.

    "For these reasons, RV merits further investigation as a potential weapon for combating the growing threat of influenza," the authors conclude.

    Snowy Owl

    In trouble to be troubled Is to have your trouble doubled. Daniel Defoe No "panic" in "pandemic."

    by Snowy Owl on Fri May 08, 2009 at 07:37:19 AM PDT

  •  Sources and Food Source of Resveratol (1+ / 0-)
    Recommended by:
    bronte17

    Sources and Food Source of Resveratol

    Heart felt thanks to Shannon an Old Timer in Flu Forums and an experts in efficient alternatives medicine duly corroborated.

    Food Sources

    Excerpts;

    Resveratrol is found in grapes, wine, grape juice, peanuts and berries of Vaccinum species including blueberries, bilberries and cranberries (73-75).

    In grapes, resveratrol is found only in the skins (76).

    The amount of resveratrol in grape skins varies with the grape cultivar, its geographic origin, and exposure to fungal infection (77).

    The amount of fermentation time a wine spends in contact with grape skins is an important determinant of its resveratrol content.

    Consequently, white and rosé wines generally contain less resveratrol than red wines (4).

    Red or purple grape juices may also be good sources of resveratrol (3).

    The predominant form of resveratrol in grapes and grape juice is trans-resveratrol glucoside (trans-piceid), but wines also contain significant amounts of resveratrol aglycones, thought to be the result of sugar cleavage during fermentation (73).

    Red wine is a relatively rich source of resveratrol, but other polyphenols are present in red wine at considerably higher concentrations than resveratrol (see the separate article on flavonoids) (79).

    The total resveratrol content of some beverages and foods are listed in the tables below. These values should be considered approximate since the resveratrol content of foods and beverages can vary considerably.

    Total Resveratrol Content of Wines and Grape Juice (3, 87, 88)
    Beverage     Total resveratrol (mg/liter)  Total
    resveratrol in a 5-oz glass (mg)

    White wines (Spanish) 0.05-1.80 0.01-0.27 Rosé wines (Spanish) 0.43-3.52 0.06-0.53 Red wines (Spanish) 1.92-12.59 0.29-1.89Red wines (global) 1.98-7.13 0.30-1.07 Red grape juice (Spanish) 1.14-8.69 0.17-1.30

    Total Resveratrol Content of Selected Foods (73, 75, 89)

    Food

    Serving Total resveratrol (mg)
    Peanuts (raw) 1 cup (146 g) 0.01-0.26
    Peanuts (boiled) 1 cup (180 g) 0.32-1.28
    Peanut butter 1 cup (258 g) 0.04-0.13
    Red grapes 1 cup (160 g) 0.24-1.25

    Supplements

    Most resveratrol supplements available in the U.S. contain extracts of the root of Polygonum cuspidatum also known as Hu Zhang or kojo-kon (80).

    Red wine extracts and red grape extracts containing resveratrol and other polyphenols are also available in the U.S. as dietary supplements.

    Resveratrol supplements may contain anywhere from 10-50 mg of resveratrol, but the effective doses for chronic disease prevention in humans are not known.

    Safety and Adverse Effects

    Resveratrol is not known to be toxic or cause adverse effects in humans, but there have been few controlled clinical trials. In rats, daily oral administration of trans-resveratrol at doses up to 300 mg/kg of body weight for 4 weeks resulted in no apparent adverse effects (81, 82).

    Pregnancy and Lactation

    The safety of resveratrol-containing supplements during pregnancy and lactation has not been established (80).

    Since no safe level of alcohol consumption has been established at any stage of pregnancy (83), pregnant women should avoid consuming wine as a source of resveratrol.

    Estrogen-sensitive Cancers

    Until more is known about the estrogenic activity of resveratrol in humans, women with a history of estrogen-sensitive cancers, such as breast, ovarian and uterine cancers, should avoid resveratrol supplements (see Estrogenic and Anti-estrogenic Activities above).

    Drug Interactions

    Anticoagulant and Antiplatelet Drugs
    Resveratrol has been found to inhibit human platelet aggregation in vitro (42, 84).

    Theoretically, high intakes of resveratrol (e.g., from supplements) could increase the risk of bleeding when taken with anticoagulant drugs, such as warfarin (Coumadin), and antiplatelet drugs, such as clodipogel (Plavix), dipyridamole (Persantine), non-steroidal anti-inflamatory drugs (NSAIDs), aspirin and others.

    References
    Written by:
    Jane Higdon, Ph.D.
    Linus Pauling Institute
    Oregon State University

    Snowy

    In trouble to be troubled Is to have your trouble doubled. Daniel Defoe No "panic" in "pandemic."

    by Snowy Owl on Fri May 08, 2009 at 07:43:11 AM PDT

  •  Resveratrol in grape juice, cranberry juice, and (1+ / 0-)
    Recommended by:
    bronte17

    Resveratrol in grape juice, cranberry juice, and in wine

    All thanks to Mingus a wonderfull Neighbors

    Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, IL 60612, USA.

    Resveratrol is an antioxidant found in grapes, grape products, and some other botanical sources with antiinflammatory and anticancer properties.

    In grapes and wine, it occurs both as free resveratrol and piceid, the 3beta-glucoside of resveratrol. Here we report a liquid chromatography-mass spectrometry method to analyze total resveratrol (including free resveratrol and resveratrol from piceid) in fruit products and wine.

    Samples were extracted using methanol, enzymatically hydrolyzed, and analyzed using reversed phase HPLC with positive ion atmospheric pressure chemical ionization (APCI) mass spectrometric detection.

    Resveratrol was detected in grape, cranberry, and wine samples. Concentrations ranged from 1.56 to 1042 nmol/g in Concord grape products, and from 8.63 to 24.84 micromol/L in Italian red wine.

    The concentrations of resveratrol were silmilar in cranberry and grape juice at 1.07 and 1.56 nmol/g, respectively.

    Snowy

    In trouble to be troubled Is to have your trouble doubled. Daniel Defoe No "panic" in "pandemic."

    by Snowy Owl on Fri May 08, 2009 at 08:05:51 AM PDT

    •  I don't know if anyone has any sense of how much (0+ / 0-)

      grape juice or wine you'd have to drink to get some protection from the flu (I don't drink wine so it'd be grape or cranberry juice for me).  But at any rate, this is very interesting information so far, and there's certainly no harm in adding some juice to the diet as long as H1N1 is around.

      THanks for the tip, Snowy Owl.

  •  Swine-bird flu bullshit... (0+ / 0-)

    It's patently obvious that this is just more of the same manufactured hysteria. Let me tell you something: it's not the swine flu, nor the bird flu, nor even the swine-bird flu, that's going to get you.

    It's the sausage, the buffalo wings, and the cordon bleu.

    That actually brings to mind a humble suggestion: henceforth, the supposed swine-bird flu shall be known as the Cordon Bleu Flu.

    Mmm... cordon bleu flu... arghh.....

    There is no such thing as "renewable energy." The universe is a non-renewable resource. Blog: The Daily Elitist

    by TylerFromNE on Fri May 08, 2009 at 08:38:15 AM PDT

  •  AJC Person-to-Person Transmission Now Common Rout (0+ / 0-)

    Person-to-Person Transmission Now Common Route for Swine Flu in U.S.

    FRIDAY, May 8 (HealthDay News) -- The number of confirmed or suspected cases of swine flu in the United States was approaching 1,900, federal health officials said late Thursday, with most new cases now caused by person-to-person transmission and not some link to Mexico, as was the case when the outbreak began nearly two weeks ago.

    "Only about 10 percent of confirmed cases have a travel history for Mexico," which is believed to be the source of the outbreak, Dr. Richard Besser, acting director of the Centers for Disease Control and Prevention, said during an afternoon teleconference. "This indicates ongoing transmission in communities. We would expect that as this [virus] travels more around the country that we are going to see that number go down. While there may have been introduction from travel to Mexico, the spread that's ongoing does not require travel to Mexico," he added.

    Besser said there were now 1,823 probable and confirmed cases in 44 states, with most of the infections mild and leading to a quick recovery.

    The median age of hospitalized individuals with swine flu is 15.

    On Thursday, the New England Journal of Medicine released early a study by CDC researchers that said 11 cases of infection with a swine flu virus similar to that involved in the current outbreak have been recorded in the United States since 2005. These viral strains were so-called "triple-reassortant" viruses, meaning that -- like the current H1N1 strain -- they contained genes from bird, pig and human viruses.

    All but two of the cases involved people who had direct or indirect contact with pigs, but "in another patient, human-to-human transmission was suspected," wrote a team led by Dr. Lyn Finelli of the CDC's Influenza Division. The patients were typically young -- with an average age of 10 years -- and four of the 11 cases were severe enough to require hospitalization, with two needing invasive mechanical ventilation. Four patients were given the antiviral medication Tamiflu and all eventually recovered, according to the report.

    At the teleconference, Besser also discussed reports of so-called swine flu parties.

    "Having swine flu H1N1 parties is a big mistake," he said.

    "This is a new emerging infection and we are learning more each day, but how an individual person will be impacted by the infection is not something we know.

    It is a big mistake.

    It is putting individuals and children at risk and CDC does not recommend that people follow that course."

    As the outbreak continues, the CDC continues to study various aspects of the health threat to gain a better understanding of the virus, how it is spread, as well as better ways to test for it, Besser said. The research under way includes: finding a rapid diagnostic test; understanding "viral shedding" (how long people can pass the virus to others); determining how the virus is transmitted in households; and learning how well antiviral drugs work, he said.

    My Indians Roots Echoe that you have no right to infect the village because You decide to infect yourself.  Go up Hill and stay there for awhile if you want to do that.

    Snowy Owl

    In trouble to be troubled Is to have your trouble doubled. Daniel Defoe No "panic" in "pandemic."

    by Snowy Owl on Fri May 08, 2009 at 08:44:23 AM PDT

  •  WHO-Influenza A(H1N1) - update 22 8 May 2009 (0+ / 0-)

    Influenza A(H1N1) - update 22

    8 May 2009 -- As of 16:00 GMT, 8 May 2009, 25 countries have officially reported 2500 cases of influenza A (H1N1) infection.

    Mexico has reported 1204 laboratory confirmed human cases of infection, including 44 deaths.

    The United States has reported 896 laboratory confirmed human cases, including two deaths.

    The following countries have reported laboratory confirmed cases with no deaths -
    Austria (1),
    Brazil (4),
    Canada (214),
    China, Hong Kong Special Administrative Region (1), Colombia (1),
    Costa Rica (1),
    Denmark (1),
    El Salvador (2),
    France (12), Germany (11),
    Guatemala (1),
    Ireland (1),
    Israel (7),
    Italy (6),
    Netherlands (3),
    New Zealand (5),
    Poland (1), Portugal (1),
    Republic of Korea (3),
    Spain (88),
    Sweden (1),
    Switzerland (1) and the
    United Kingdom (34).

    WHO is not recommending travel restrictions related to the outbreak of the influenza A(H1N1) virus.

    Individuals who are ill should delay travel plans and returning travelers who fall ill should seek appropriate medical care. These recommendations are prudent measures which can limit the spread of many communicable diseases, including influenza.

    Further information on the situation will be available on the WHO website on a regular basis.

    In trouble to be troubled Is to have your trouble doubled. Daniel Defoe No "panic" in "pandemic."

    by Snowy Owl on Fri May 08, 2009 at 01:50:00 PM PDT

  •  CDC offers new details on swine flu cases (0+ / 0-)

    CDC offers new details on swine flu cases

    Robert Roos  News Editor

    May 7, 2009 (CIDRAP News) – In their most detailed profile of H1N1 swine influenza cases so far, federal health officials reported today that only 5% of US patients were older than 50 and that 38% of patients had gastrointestinal problems, well above what's typical for seasonal flu.

    The report by the Centers for Disease Control and Prevention (CDC) also says that 9% of patients for whom details were available were hospitalized and that more than half of the patients who had severe cases had typical risk factors for complications from seasonal flu.

    Age range and possible reasons
    Reporting on the 642 confirmed US cases reported through May 5, the CDC says that 60% of patients were younger than 19, 40% were between 10 and 18, and only 5% were 51 or older. For cases with available data, 18% of patients had traveled to Mexico, and 16% were connected to school outbreaks.

    The CDC says the predominance of younger patients suggests several possibilities: that young people are more susceptible to the virus; that differences in social networks have delayed transmission to older people; that older people have some cross-protection from existing antibodies; or that more young people are being tested because of outbreaks in schools.

    The most common signs of illness were fever (94% of patients), cough (92%), and sore throat (66%), the report says. In addition, 25% of patients had diarrhea and the same fraction had vomiting. In all, 38% of patients had one or both gastrointestinal problems, "neither of which is typical of seasonal influenza," the report states.

    "Because of this observation, we are recommending that clinicians think about transmission not only through the respiratory route but also through the gastrointestinal route, through fecal-oral transmission," said Fatimah S. Dawood, MD, first author of the report, in a CDC teleconference today.

    Novel Swine-Origin Influenza A (H1N1) Virus Investigation Team. Emergence of a novel swine-origin influenza A (H1N1) virus in humans. N Engl J Med 2009 Jul 2; early online edition;361 [Full text]

    Belshe RB. Implications of the emergence of a novel H1 influenza virus (editorial). N Engl J Med 2009 Jul 2; early online edition;361 [Full text]

    Snowy Owl

    In trouble to be troubled Is to have your trouble doubled. Daniel Defoe No "panic" in "pandemic."

    by Snowy Owl on Sat May 09, 2009 at 02:40:33 AM PDT

  •  'Worried well' overload gives taste of pandemic s (0+ / 0-)

    'Worried well' overload gives taste of pandemic scenario

    Maryn McKenna  Contributing Writer

    Apr 8, 2009 (CIDRAP News) –

    With the global outbreak of novel H1N1 influenza (swine flu) entering its fourth week, physicians at emergency rooms, clinics, and hospitals around the United States say they are overwhelmed with "worried well" who have as much as doubled their patient loads.

    All the clinicians work at medical centers that have planned and practiced for pandemics and disasters. But the crisis has exposed a weak point that their preparation could not influence: a crush of fearful patients seeking reassurance, many of them sent to emergency rooms (ERs) for tests by workplaces, schools, and busy primary care physicians.

    Those who have been dealing with the onslaught say it should serve as a warning. If this flu strain or another becomes more virulent—causing more serious disease than it now does, and presumably also inspiring more panic—the healthcare system will not be able to handle the demand.

    "We are going to have to develop screening and triage systems that are not dependent on hospitals and emergency departments, or hospitals and emergency departments are going to be totally overwhelmed," said Dr. Edward Panacek, a professor of emergency medicine at University of California-Davis Medical Center, where ER volume has been running significantly above normal.

    The same concerns are echoing through listservs used by pediatric emergency physicians, with many institutions seeing "50% to 75% increases," said Dr. Stuart Bradin, an assistant professor of pediatrics and emergency medicine at the University of Michigan Health System. At the university's main site in Ann Arbor, "there are definitely more parents who bring kids in for a cold or a low-grade temperature who might have stayed home or called their own primary care physician but are now coming in to 'make sure its not swine flu,'" he said by e-mail.

    Fine Tuning on Parental Guidance is needed to avoid overcrowding of Health care Officine is needed.  Informing the parents to recognised the symptoms, on how to swiftly personnally intervene (with pertinent informations of course) is becoming as must for all and in printed forms.

    I have ask many time to the Secretaries of Health, to Ministers of Health of different countries on the reasons why we still do not have received PRINTED documents about this.

    Their answers are base mainly on two motives.

    First there are legal considerations and second, the auto-care concept violates the authority of the Medical Corpus.

    A new Ethical Protocol should be at least volontarely adopted when a society is in a Public Crisis.

    BTWm the same should apply on copyrights.

    New England Journal of Medicine, the Lancet in UK and Institut Pasteur have adopted a Public Health response to this matter by making accessible informations freely to all and tolerate traditional copyrights breachs. Tolerance for the sake of Public Health.

    The Main Stream Medias should follow the same Panth and declare that in consideration of Public Health, amidst a Public Health crisis, written authorisation below articles should states that they abandonned copyrights in this specific field.

    I would like to share with you one personnal/collective experience to show how such a consensual policy can make a huge difference and how can induce
    the reduction of morbidity and mortality to unimaginable scale.

    Few years ago, an outbreak of a know virus (Chickungunya) happened in an France isolate archipelo in the Indian Ocean, the Reunion Island.

    Reunion island has a population of about 750 000 people and about 50% got infected by the Chick, a virus transmitted by mosquitos and whose symptoms would litterally make one person in pain and unable to do daily activity for up to two weeks sometimes.  While Reunion Island Doctors called for help the Pasteur Institute of Lyon France decided to share their infos with la Reunion.

    Then I received a request from a Province Health Minister of India that has been convinced by his Health Experts to immediatly implement preventive measures to protect a total of 320 millions people in three Provinces of India.

    I then translate from French to English the informations about the outbreak of La Reunion and the results of the Pasteur Institute.

    Some measures where then swiftly done in India and at least in these three provinces morbidity and mortality cause by the Chick virus went way down.

    Something Main Stream Media and Website Forums should refer to.

    Public Health transcend mere lucrative, notoriety or traditional interests. its interest, by nature should be Public Health towards huge amount of population interests.  Ain<t that what Humanitarian approach is about???</p>

    Snowy Owl

    In trouble to be troubled Is to have your trouble doubled. Daniel Defoe No "panic" in "pandemic."

    by Snowy Owl on Sat May 09, 2009 at 03:19:30 AM PDT

  •  Communicating the Flu (0+ / 0-)

    Communicating the Flu

    Nedra Weinreich is a consultant, author and speaker who uses social marketing to promote health and social issues for nonprofits and public agencies at Weinreich Communications.

    She was a invited blogger on the HHS Pandemic Flu Leadership Blog in 2007

    At that time, a pandemic seemed like a far-off risk, though we knew it was more a question of 'when' than 'if.'

    Since then, HHS and CDC have been working hard to increase preparedness at the national, state and local levels.

    From the rapid and effective response we've seen so far, it appears that they have done good work in that arena.

    Health departments and school districts in the US, and especially in Mexico City, have been quick to identify cases, isolate them and implement social distancing measures to keep people away from each other.

    But I'd hoped we would have been further along prior to a pandemic in the areas of public awareness and preparedness.

    I'm currently involved in the social media piece of a CDC contract that is building grassroots coalitions to increase pandemic preparedness at the community level.

    Here are her recomendations;

    Build on the new awareness of pandemic flu to take people to the next level.

    HHS and the media have both done a good job of pushing handwashing, avoiding sneezing into hands, and staying home when sick.

    We can now move past the "what is pandemic flu" and go directly to "how can I prevent and prepare for a pandemic?"

    We may have a window of opportunity for individuals and families to begin the process of gathering the supplies they would need in the case of an extended severe pandemic to survive at home sheltering in place.

    I think that HHS did a good thing by not emphasizing the need to stockpile food while we were in the thick of the beginning of the outbreak, thereby avoiding panic and shortages.

    But once the danger has passed, messages about slowly but steadily building up a supply of food, water and medical supplies must begin. (Here is an excellent pdf guide to pandemic preparedness and response.)

    Complacency is a real danger. Messages should make the point that a severe pandemic remains a real possibility and that prevention measures kept this H1N1 virus in check.  Messages should emphasize how being prepared puts you in control. During turbulent times, giving people steps they can take to prevent or mitigate problems makes them feel empowered and capable. That's what we need!

    Emphasize that being prepared for a pandemic will benefit them for many other types of disasters as well.

    Many of the same recommendations for food, water and medical supplies apply for regional hazards like earthquakes, hurricanes, tornadoes, and floods. It never hurts to be prepared, and often helps.

    Continue to use social media to monitor what people are saying about pandemic flu-related issues. This can give you an idea of incorrect information or rumors that are being passed around, or the questions that keep coming up that need to be answered.

    We now have an opportunity to keep the pace in promoting preparedness and present options to motivate and help people on how it can be done.

    Snowy Owl

    In trouble to be troubled Is to have your trouble doubled. Daniel Defoe No "panic" in "pandemic."

    by Snowy Owl on Sat May 09, 2009 at 04:16:34 AM PDT

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