Skip to main content

The Wall Street Journal reported July 9, 2010, that there's been an Advance in Quest for HIV Vaccine. Although it may take years to develop a vaccine, finding antibodies to the set of HIV viruses that cause AIDS is a gigantic step forward.

NOTE: This has been diaried before, here and here, but I think it's important enough news to diary again so that more people will see it. The announcement is not for a cure for AIDS, nor is it a vaccine. Yet. It's just a big advance in the field.

HIV/AIDS is a tough virus to immunise against or kill once it's in the body. Most antibodies don't work on all strains of HIV - the virus is very mutable, which means it changes a lot (the flu is another highly mutable virus). In fact, most antibodies only work on a couple of strains. The antibodies found in the Vaccine Research Center at the National Institute of Allergy and Infectious Diseases study work on more than 90% of HIV strains. These newly found antibodies bind to a different place on the HIV virion than other antibodies, allowing them to neutralise many more HIV strains. Previous antibodies have worked on, at best, about 40% of HIV types.

Science magazine has the abstract online for free. The full article is behind a paywall.

Make no mistake - this is not a solution for any of the problems associated with HIV. It doesn't solve transmissibility. It doesn't cure those infected with HIV and it doesn't help AIDS patients or people living with HIV. It doesn't prevent infection with HIV. It does, however, provide hope for future improvements in dealing with the AIDS epidemic.

Originally posted to SciMathGuy on Fri Jul 09, 2010 at 09:12 AM PDT.


This is:

71%130 votes
19%36 votes
2%5 votes
3%7 votes
2%5 votes

| 183 votes | Vote | Results

Your Email has been sent.
You must add at least one tag to this diary before publishing it.

Add keywords that describe this diary. Separate multiple keywords with commas.
Tagging tips - Search For Tags - Browse For Tags


More Tagging tips:

A tag is a way to search for this diary. If someone is searching for "Barack Obama," is this a diary they'd be trying to find?

Use a person's full name, without any title. Senator Obama may become President Obama, and Michelle Obama might run for office.

If your diary covers an election or elected official, use election tags, which are generally the state abbreviation followed by the office. CA-01 is the first district House seat. CA-Sen covers both senate races. NY-GOV covers the New York governor's race.

Tags do not compound: that is, "education reform" is a completely different tag from "education". A tag like "reform" alone is probably not meaningful.

Consider if one or more of these tags fits your diary: Civil Rights, Community, Congress, Culture, Economy, Education, Elections, Energy, Environment, Health Care, International, Labor, Law, Media, Meta, National Security, Science, Transportation, or White House. If your diary is specific to a state, consider adding the state (California, Texas, etc). Keep in mind, though, that there are many wonderful and important diaries that don't fit in any of these tags. Don't worry if yours doesn't.

You can add a private note to this diary when hotlisting it:
Are you sure you want to remove this diary from your hotlist?
Are you sure you want to remove your recommendation? You can only recommend a diary once, so you will not be able to re-recommend it afterwards.
Rescue this diary, and add a note:
Are you sure you want to remove this diary from Rescue?
Choose where to republish this diary. The diary will be added to the queue for that group. Publish it from the queue to make it appear.

You must be a member of a group to use this feature.

Add a quick update to your diary without changing the diary itself:
Are you sure you want to remove this diary?
(The diary will be removed from the site and returned to your drafts for further editing.)
(The diary will be removed.)
Are you sure you want to save these changes to the published diary?

Comment Preferences

  •  NIH ramping up for clinical trials (5+ / 0-)

    Looks like the NIH is ramping up for larger trials. On February 26, it requested bids to produce the antibody for pre-clinical and clinical trials.

    "I had seen the universe as it begins for all things. It was, in reality, a child's universe, a tiny and laughing universe." Loren Eiseley

    by cadejo4 on Fri Jul 09, 2010 at 09:32:19 AM PDT

  •  Thanks for publicizing this, SMG! (6+ / 0-)

    Frugal Fridays, where the cheap come to chat.

    by sarahnity on Fri Jul 09, 2010 at 09:44:40 AM PDT

  •  I was reading the L.A. Times article as you (4+ / 0-)
    Recommended by:
    sarahnity, Floja Roja, MsWings, SciMathGuy

    posted this. Great news indeed.

  •  A Roadmap For An AIDS Vaccine Was Published (3+ / 0-)
    Recommended by:
    Floja Roja, SciMathGuy, rsmpdx

    years ago.

    But nobody was interested as far as I can tell.

    Huh? What? Why not?

    Takes a little telling.

    It's about sugar.

    A kind lots of people think they know all about but don't.  Nobody does.

    You see the HIV retrovirus uses sugar to hide just like cancer and other diseases do.

    That sugar pattern is distinct.

    Knowing the sugar pattern provides a target.

    Glycobiologists know a bit about sugar.  Not much but a little.

    There aren't many glycobiologists and the ones there are mostly talk to themselves because the language is foreign to normal people, even scientists who think they know a lot about sugar.

    And so we do immunology and cellular biology, which are not all that good.  Better than nothing. You do what you can.

    Sure hope things work.

    But it might help if we spent more money killing disease and less money killing people.

    One might say that would be very sweet.

    The book is here for any that have too much money and that for some reason are interested in killing disease instead of killing people.

    I apologize in advance for any thought I want to hijack this thread.  I don't.  Again I wish success with an incredibly difficult task by any who try.

    Best,  Terry

    •  Not hijacked. (2+ / 0-)
      Recommended by:
      Floja Roja, rsmpdx

      Making drugs aimed at carbohydrates is another approach to treating some diseases.

      Generally, vaccines try to mimic the agent you're vaccinating against, so whole live attenuated (weakened) organisms or killed organisms are used. Sometimes, treatments can be made that allow the body to focus on a part of the organism rather than the whole thing. Antibodies generally require a protein to bind to so that the offending organism can be "neutralised," but other approaches have been tried, too.

      -8.75, -6.72 If it's 15000 ft below sea level, maybe it should stay there.

      by SciMathGuy on Fri Jul 09, 2010 at 10:30:10 AM PDT

      [ Parent ]

      •  A Scottish Immunologist Gave A Short Lecture In (1+ / 0-)
        Recommended by:

        Florida on a carbohydrate cancer vaccine she was working on.

        I asked a very distinguished and knowledgeable lady with considerable accomplishments why she thought her vaccine would work while another similar vaccine had failed miserably in a Phase III trial and been abandoned.

        I have no memory of the details of her reply.  Probably had my mind on seeing other ladies on the beach in Florida.  Essentially I think she talked about better targeting.

        A few weeks later her vaccine was abandoned.

        My guess is that she and the other guys' problem was that they didn't really understand carbohydrates.

        As I indicated those dang glycobiologists speak really funny.  I know because I tried to talk them too.  Even the American ones talk a strange language.

        Take care, my friend.  We all must swim in a sea of ignorance.

        Just on its face, fighting a retrovirus that hijacks the immune system for its own purposes with immunology is a devilishly difficult problem.

        Best,  Terry

        •  Amen to that! (0+ / 0-)

          fighting a retrovirus that hijacks the immune system for its own purposes with immunology is a devilishly difficult problem.

          Yep - that is a real booger! Viruses are problems. Retroviruses are worse problems. Retroviruses that kill the immune system are almost unspeakable problems.

          -8.75, -6.72 If it's 15000 ft below sea level, maybe it should stay there.

          by SciMathGuy on Fri Jul 09, 2010 at 11:37:21 AM PDT

          [ Parent ]

Meteor Blades, JD SoOR, Sharoney, a gilas girl, Rebecca, Mark Sumner, Greg Dworkin, claude, Renee, Sharon, Velocity, JekyllnHyde, Angie in WA State, Joe Bob, jo fish, molly bloom, CJB, Ray Radlein, Brainwrap, TealVeal, murphy, copymark, hyperbolic pants explosion, deben, jennybravo, Trendar, David, Cali Scribe, asimbagirl, NevDem, TrueBlueMajority, Dave the Wave, tiponeill, mem from somerville, kainah, Reino, KLM, RunawayRose, scrape, tnichlsn, alicia, ChicDemago, Cvstos, waytac, ThatTallGuy, rhubarb, oysterface, eeff, Mnemosyne, rubyr, Andrew M, dsb, moira977, xynz, StevenJoseph, bspector, Woody, dash888, SallyCat, Ahianne, expatjourno, nanoboy, lady sisyphus, ssgbryan, checkmate, cinnamon68, jackspace, entlord, DanD, TheMomCat, bronte17, TravnTexas, sciencegirl, 88kathy, susans, justme, cskendrick, fugwb, BlackSheep1, Wee Mama, mint julep, Euroliberal, sarahnity, nyceve, pucklady, bhlogger, djMikulec, Loquatrix, Agathena, Kevvboy, JFKinSoDak, CoolOnion, ShadowRunning, RabidNation, mikidee, stevej, chuckvw, Bensdad, Glic, shanikka, phillies, Dburn, Dante Atkins, otto, JJG Miami Shores, AndyT, roses, BuckMulligan, Ignacio Magaloni, sberel, Clues, Larry Bailey, itsmitch, limae, Miss Blue, jennifree2bme, itskevin, bwren, TampaCPA, Cedwyn, djdissent, odenthal, Eddie C, wader, sviscusi, Janeo, nio, revsue, jdmorg, byebyeblinkie, tomephil, dangoch, menodoc, VexingEyes, psnyder, BleacherBum153, TexDem, Dallasdoc, Kamakhya, figbash, pat bunny, 2laneIA, milton333, TiaRachel, chriscol, cosette, PaulVA, churchylafemme, texasmom, HeyMikey, chrismorgan, NYFM, flatford39, Jujuree, CarbonFiberBoy, penguins4peace, 42, Chirons apprentice, johnnygunn, On The Bus, defluxion10, houyhnhnm, nika7k, rockhound, Tillie630, annetteboardman, rlharry, RenaRF, Timbuk3, Dood Abides, barbwires, Dave925, Bendra, Matt Esler, zett, Curt Matlock, Kitsap River, zadarum, Steven D, leftover, DarkSyde, Albanius, Pam LaPier, BigDuck, rickeagle, babaloo, TexMex, TexH, tardcat, vcmvo2, Skennet Boch, Desert Rose, Bluesee, radarlady, capelza, NoMoreLies, Hoomai29, Jeffersonian Democrat, Unit Zero, yuriwho, klamothe, irate, Technowitch, Jersey Girl, Alice Venturi, bagman, run around, elkhunter, ajsuited, citizenx, basquebob, dewtx, ChemBob, zamrzla, Brooke In Seattle, J Rae, YucatanMan, kartski, ratzo, majcmb1, sallyfallschurch, judy99, chancew, GTPinNJ, GreyHawk, ladybug53, Kayakbiker, eaglecries, sheddhead, quaoar, Phil S 33, BayAreaKen, blue jersey mom, govib, Sandino, kaliope, Ozzie, power model, Floja Roja, kerplunk, Shaking the Tree, Red Bean, Rogneid, JanL, Ekaterin, hcc in VA, roubs, psyched, JanF, Brubs, Snud, terjeanderson, noweasels, ThatSinger, begone, lcork, StrangeTikiGod, RiaD, jiordan, Mother Mags, elliott, Showman, BachFan, Orinoco, tarheelblue, Patriot Daily News Clearinghouse, highfive, Pinko Elephant, localroger, vigilant meerkat, Black Knight, ej25, tobendaro, dharmafarmer, tonyahky, ActivistGuy, koNko, martyc35, Triscula, mango, Naniboujou, Albatross, fiddler crabby, fou, kck, neecie100, blueoasis, Conceptual Guerilla, triv33, birdbrain64, dyttocs, twigg, 4Freedom, bubbanomics, nonnie9999, gooderservice, Crashing Vor, thegood thebad thedumb, mithra, JVolvo, NearlyNormal, CTLiberal, bleeding heart, dilireus, Preston S, boatsie, sceptical observer, ER Doc, webgenie, Turbonerd, AmBushed, engine17, JugOPunch, Unknown Quantity, doingbusinessas, Clive all hat no horse Rodeo, agent, Texdude50, Dreaming of Better Days, blueoregon, 1864 House, equern, Zoskie, FrankieB, lily bart loves her soma, HGM MA, thatvisionthing, Friend of the court, Hedwig, Temmoku, ipsos, postmodernista, blueintheface, AllanTBG, markthshark, Little, HM2Viking, pale cold, One Pissed Off Liberal, tonyfv, bear83, bluicebank, Cali Techie, BeninSC, anotherdemocrat, dotsright, donnamarie, Loudoun County Dem, greytdog, FWIW, milkbone, ninkasi23, gloriana, Positronicus, VClib, terryhallinan, psychodrew, edsbrooklyn, FishOutofWater, Sydserious, Trial Lawyer Richard, Mary Mike, Mark E Andersen, some other george, flumptytail, operculum, dclawyer06, joyful, Unbozo, newpioneer, RosyFinch, jayden, second gen, cyncynical, cadejo4, stcroix cheesehead, jnhobbs, Bronx59, jhop7, gchaucer2, NorthlandLiberal, yella dawg, Chico David RN, Zydekos, asinine, trueblueliberal, dizzydean, vet, DGreenCPA, oddstray, on the cusp, roycej, Empower Ink, roberta g, Blue Boy Red State, msblucow, Amor Y Risa, mconvente, Devsd, edg, also mom of 5, JeffW, ChocolateChris, greenalley, Chacounne, wayoutinthestix, ScottyUrb, zerone, Senor Unoball, East Village Blue, Involuntary Exile, bythesea, theunreasonableHUman, skohayes, filby, blindyone, ajr111240, lineatus, Sharon Wraight, VL Baker, Deep Harm, Calamity Jean, Cassandra Waites, pickandshovel, bluesheep, Missys Brother, MsWings, catly, envwq, S C B, Gemina13, Horsefeathers, kyril, brokensnowshoe, Parthenia, AlBob, tethys, allie123, rodentrancher, magicsister, joe joe, ekyprogressive, Ellinorianne, HoosierDeb, dmhlt 66, watercarrier4diogenes, jlms qkw, Leo in NJ, squarewheel, woodtick, oldliberal, LaFeminista, Celtic Merlin, satanicpanic, Old Woman, Design the Future, dreamghost, maggiejean, MsMadrigal, McGahee220, smellybeast, J M F, Fonsia, Fogiv, rsmpdx, ARS, rcnewton, snackdoodle, juca, carolyn urban, seanwright, cantelow, bondibox, Stranded Wind, RandomActsOfReason, Gorilla in the room, janmtairy, h bridges, jontabb, shopkeeper, EquationDoc, unspeakable, Bindle, richrichthanki, geebeebee, marzook, MKSinSA, NWTerriD, asym, oxfdblue, Alise, lastman, Denise Oliver Velez, Keith Pickering, conlakappa, Kysen, mikeplugh, louisev, nancat357, Dragon5616, astral66, Tommymac, citisven, French Imp, Larsstephens, Vermfly, Just Bob, cricket456, Its the Supreme Court Stupid, commonmass, YellerDog, RhymesWithUrple, OrangeMike, rb137, trustno1, flitedocnm, Jez, TFinSF, awesumtenor, Vacationland, LaughingPlanet, eXtina, PZinOR, politik, princss6, catwho, kjoftherock, boriquasi, birddog, freeport beach PA, Klaus, BoxNDox, batchick, gulfgal98, pixxer, Puddytat, Mariken, dlemex, juturna, 2020adam, ThisIsMyTime, DiegoUK, Yasuragi, Publius2008, Texnance, Betty Pinson, Unenergy, orlbucfan, science nerd, Oh Mary Oh, HylasBrook, farrelad, Vega, rmabelis, NellaSelim, ciganka, translatorpro, no way lack of brain, Onomastic, Jane Lew, annieli, tharu1, BrowniesAreGood, Maximilien Robespierre, Jasel, Colorado is the Shiznit, angstall, meralda, Hill Jill, kamrom, Matthew D Jones, salientwhisper, Les Common, ToeJamFootball, Bob Duck, yesdevkmem, ban nock, Hopeful Skeptic, jardin32, thebluecrayon, kirbybruno, cv lurking gf, myadestes, cooper888, sophiedaisey, gbinwc, thinkmoss, Eclectablog, FarWestGirl, BlueHead, doug1204, itzik shpitzik, beantown mom, Ebby, feeny, Josiology, mrsgoo, Donna O, marleycat, Shes a Riot, cyberpuggy, Escamillo, Muskegon Critic, marigold, hikerbiker, midnight lurker, rk2, jhb90277, tardis10, nogo postal, Carbunkle Rugburn, Wide Awake in KY, enhydra lutris, EsperanzaCambia, whaddaya, sound of progress, Wood Dragon, cap76, kid funkadelic, lincoln deschain, Niphead, Badjuh, blue aardvark, Miggles, kareylou, Book of Hearts, Ezekial 23 20, joanbrooker, mrami, Regina in a Sears Kit House, Mentatmark, CoyoteMarti, AgentOfProgress, erush1345, StPeteDave, No one gets out alive, DawnN, Dom9000, BlueDragon, YaNevaNo, brown and blue all over, Pinto Pony, Patric Juillet, yawnimawke, ridemybike, wretchedhive, Barbie02360, angry marmot, Siri, We Won, IndieGuy, Eric Nelson, msrevis, oneshot, AnnieR, TomorrowsProgressives, Horace Boothroyd III, shanesnana, David Kroning II, TheLandstander, Mike RinRI, hotheadCA, belinda ridgewood, supercereal, Ana Thema, radical simplicity, My Name Isnt Earl, aznavy, OllieGarkey, absolute beginner, Fed up Fed, wxorknot, tytalus, GDbot, PerpetualMind, Denver11, jeannew, Kinak, Glen The Plumber, George3, Villanova Rhodes, evergreen2, mumtaznepal, BradyB, Portlaw, mythatsme, Raven Song, Lizabet, allensl, Lightbulb, SwedishJewfish

Subscribe or Donate to support Daily Kos.

Click here for the mobile view of the site