Without going into any great detail, Hillary owns the word ignorant, first and foremost, not in the sense of being unintelligent, but in the way of ignoring the welfare of others. In the pejoratiive sense, Hillary is ignorant.
To merit the term "bitch" one has to act in a certain abrasive, aggressive, vindictive manner over time. I think she's earned it.
But together the words are damning. To be known as an ignorant bitch means you are done politically. You are in the process of losing friends and allies. You are without honor.
This lack of honor cannot be escaped. Not when it has been viewed publicly over time. She has burned a hole in the consciousnes of the US. Her antics will not be forgotten. In fact, I believe that she will create a new genre of literature. She will be the subject of volumes of books over the next year which will lead to further publications in the years that follow. The Hillary phenomenon will be dissected, investigated, used and taught in political science classes as what not to do, how not to act, who not to be, etc.