With Massachusetts Governor Mitt Romney (R) declaring he is not seeking a second term next year, I figured it's time for a quick rundown:
Likely Dem pickups - Massachusetts open seat (Reilly defeats Healey), New York open seat (Spitzer defeats Weld or Golisano)
50% chance or better of Dem pickup - Arkansas open seat (Beebe defeats Hutchinson), California (Angelides defeats Schwarzenegger), Maryland (O'Malley defeats Ehrlich), Ohio open seat (Strickland defeats Blackwell)
Toss-Up - Alaska (???), Colorado open seat (Beauprez vs. Ritter or Romanoff), Florida open seat (Crist or Gallagher vs. Davis), Illinois (Blagojevich vs. Topinka), Iowa (Culver vs. Nussle), Nevada (Gibbons vs. Titus)
No strong chances for GOP pickups other than Illinois and Iowa, both of which remain toss-ups.